Tag | Content |
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CPLM ID | CPLM-007677 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 |
Protein Synonyms/Alias | |
Gene Name | Gng7 |
Gene Synonyms/Alias | Gngt7 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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60 | PASENPFKDKKPCII | ubiquitination | [1] |
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Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity). |
Sequence Annotation | MOD_RES 2 2 N-acetylserine (By similarity). MOD_RES 65 65 Cysteine methyl ester (By similarity). LIPID 65 65 S-geranylgeranyl cysteine (By |
Keyword | Acetylation; Cell membrane; Complete proteome; Lipoprotein; Membrane; Methylation; Prenylation; Reference proteome; Transducer. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 68 AA |
Protein Sequence | MSGTNNVAQA RKLVEQLRIE AGIERIKVSK ASSELMSYCE QHARNDPLLV GVPASENPFK 60 DKKPCIIL 68 |
Gene Ontology | GO:0005834; C:heterotrimeric G-protein complex; NAS:RGD. GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. GO:0001662; P:behavioral fear response; IEA:Compara. GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro. GO:0007626; P:locomotory behavior; IEA:Compara. GO:0007168; P:receptor guanylyl cyclase signaling pathway; IEA:Compara. GO:0045761; P:regulation of adenylate cyclase activity; IEA:Compara. |
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Pfam | |
SMART | |
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PRINTS | |