CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013858
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Testis-specific H1 histone 
Protein Synonyms/Alias
 Haploid germ cell-specific nuclear protein 1; Histone H1t2 
Gene Name
 H1fnt 
Gene Synonyms/Alias
 Hanp1 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
310EQQYVSAKEQEYVRTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone- protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1 (By similarity). 
Sequence Annotation
  
Keyword
 ATP-binding; Chromosome; Coiled coil; Complete proteome; Developmental protein; Differentiation; DNA condensation; DNA-binding; Nucleotide-binding; Nucleus; Reference proteome; Spermatogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 418 AA 
Protein Sequence
MAEAAQPTGE SQGAELTIQI QQPVERALRT PVRRGAQSVL RVSQLLLRAI AGHQRLTLAA 60
LKKELGNAGY EVRRKISSHQ AGDSTRSEKY TLLRVSGSDA AGYFRVWKIS KPRRKAPRSR 120
LTLGSHSHGK TVLKSPRPLR PRSRRKAAKK AREVWRRKAR ALKARSRRAR SLARSMVRSR 180
ASSRASSRAR SRARSRARSR ARSRARSRAS SRARSSARSS ARSSARSSVR SSVRSSARSS 240
ARSSIRSRAR SRARTRARSR AKDLVRSKAR EQARTRAREQ AHARARTHDC VRAKAQEYVR 300
AKEQQYVSAK EQEYVRTKEQ ECAKAREQMR IGAMEEARIK AIDNRVQTTM EDTSPWSTDE 360
MRSRTKPREE KRQEPERPVK QTNQKPAVVK VDNAPSRQGK TCTKSSTKSG HPGCSGTS 418 
Gene Ontology
 GO:0000790; C:nuclear chromatin; ISS:UniProtKB.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0035092; P:sperm chromatin condensation; ISS:UniProtKB.
 GO:0007290; P:spermatid nucleus elongation; ISS:UniProtKB. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS