CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035743
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cytochrome P450 2C7 
Protein Synonyms/Alias
  
Gene Name
 LOC100361547 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
93ALIDNGEKFSGRGSYacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 490 AA 
Protein Sequence
MDLVTFLVLT LSSLILLSLW RQSSRRRKLP PGPTPLPIIG NFLQIDVKNI SQSLTKFSKT 60
YGPVFTLYLG SQPTVILHGY EAIKEALIDN GEKFSGRGSY PMIENVTKGF GIVFSNGNRW 120
KEMRRFTIMT FRNLGIGKRN IEDRVQEEAQ CLVEELRKTK GSPCDPSLIL NCAPCNVICS 180
ITFQNHFDYK DKEMLTFMEK VNENLKIMSS PWMQVCNSFP SLIDYFPGTH HKIAKNINYM 240
KSYLLKKIEE HQESLDVTNP RDFVDYYLIK QKQANNIEQS EYSHENLTCS IMDLIGAGTE 300
TMSTTLRYAL LLLMKYPHVT AKVQEEIDRV IGRHRSPCMQ DRKHMPYTDA MIHEVQRFIN 360
FVPTNLPHAV TCDIKFRNYL IPKGTKVLTS LTSVLHDSKE FPNPEMFDPG HFLDENGNFK 420
KSDYFLPFSA GKRACVGEGL ARMQLFLFLT TILQNFNLKS LVQPKDIDTR PVLNGFASLP 480
PTYQLCFIPS 490 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00463; EP450I.
 PR00385; P450.