CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023543
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Insulin-like peptide INSL6 
Protein Synonyms/Alias
 Insulin-like peptide 6; Insulin-like peptide INSL6 B chain; Insulin-like peptide INSL6 A chain 
Gene Name
 Insl6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
136KPYVKSVKFQKKNTDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 May have a role in sperm development and fertilization. 
Sequence Annotation
 DISULFID 33 169 By similarity.
 DISULFID 45 182 By similarity.
 DISULFID 168 173 By similarity.  
Keyword
 Cleavage on pair of basic residues; Complete proteome; Disulfide bond; Hormone; Reference proteome; Secreted; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 188 AA 
Protein Sequence
MKQLCCSCLL WLGLLLAPFS QEQEEVTSPT KLCGRDLLVE VIKLCGQNDW SRFSMEEQSP 60
MTELVPQYTR KVKTFNPHRS SSSWGRFTNP GVSQKKATHT WESQSLPNYQ LKKEELLPKT 120
GVHSYHGGKP YVKSVKFQKK NTDKMSTFSG LFWGNHPQRK RRGFADKCCA IGCSKEELAV 180
ACLPFVDF 188 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0006915; P:apoptotic process; IEA:Compara.
 GO:0009566; P:fertilization; IEA:Compara.
 GO:0008584; P:male gonad development; IEA:Compara.
 GO:0035264; P:multicellular organism growth; IEA:Compara.
 GO:0030317; P:sperm motility; IEA:Compara.
 GO:0007286; P:spermatid development; IEA:Compara. 
Interpro
 IPR016179; Insulin-like.
 IPR017100; Insulin-like_pep_6.
 IPR022353; Insulin_CS. 
Pfam
 PF00049; Insulin 
SMART
 SM00078; IlGF 
PROSITE
 PS00262; INSULIN 
PRINTS