CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027693
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 E1A-binding protein 
Protein Synonyms/Alias
 Protein Ep300 
Gene Name
 Ep300 
Gene Synonyms/Alias
 p300 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
292LSPFAMDKKAVTGGGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 353 AA 
Protein Sequence
MAENVVEPGP PSAKRPKLSS PALSASASDG TDFGSLFDLE HDLPDELINS TELGLTNGGD 60
ISQLQTSLGI VQDAASKHKQ LSELLRSGSS PNLNMGVGGP GQVMASQAQQ NSPGLSLINS 120
MVKSPMAQTG LTSPNMGMGS SGPNQGPTQS TAGMMNSPVN QPAMGMNTGM NAGMNPGMLA 180
AGNGQGIMPN QVMNGSIGAG RGRPNMQYPN AGMGNAGSLL TEPLQQGSPQ MGGQPGLRGP 240
QSHKMGMMSN PTPYGSPYTQ NSGQQIGASG LGLQIQTKTV LPNNLSPFAM DKKAVTGGGM 300
PNMGQQPTPS VQQPGLVNPV APGMGSGAHT ADPEKRKLIQ QQLVLLLHAH KCQ 353 
Gene Ontology
 GO:0000785; C:chromatin; IDA:RGD.
 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0000123; C:histone acetyltransferase complex; IEA:Compara.
 GO:0032993; C:protein-DNA complex; IDA:RGD.
 GO:0005667; C:transcription factor complex; IC:RGD.
 GO:0003823; F:antigen binding; IDA:RGD.
 GO:0031490; F:chromatin DNA binding; IDA:RGD.
 GO:0001047; F:core promoter binding; IEA:Compara.
 GO:0035259; F:glucocorticoid receptor binding; IDA:RGD.
 GO:0004402; F:histone acetyltransferase activity; IMP:RGD.
 GO:0004468; F:lysine N-acetyltransferase activity; IMP:RGD.
 GO:0042975; F:peroxisome proliferator activated receptor binding; IDA:RGD.
 GO:0032403; F:protein complex binding; IDA:RGD.
 GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:RGD.
 GO:0003713; F:transcription coactivator activity; IEA:Compara.
 GO:0008134; F:transcription factor binding; IDA:RGD.
 GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.
 GO:0048565; P:digestive tract development; IEP:RGD.
 GO:0007507; P:heart development; IEA:Compara.
 GO:0043967; P:histone H4 acetylation; IEA:Compara.
 GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Compara.
 GO:0001889; P:liver development; IEP:RGD.
 GO:0030324; P:lung development; IEA:Compara.
 GO:0018076; P:N-terminal peptidyl-lysine acetylation; IEA:Compara.
 GO:0031324; P:negative regulation of cellular metabolic process; IMP:RGD.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0009887; P:organ morphogenesis; IEA:Compara.
 GO:0043923; P:positive regulation by host of viral transcription; IEA:Compara.
 GO:0045773; P:positive regulation of axon extension; IMP:RGD.
 GO:0045793; P:positive regulation of cell size; IMP:RGD.
 GO:0032967; P:positive regulation of collagen biosynthetic process; IMP:RGD.
 GO:0043388; P:positive regulation of DNA binding; IMP:RGD.
 GO:0010560; P:positive regulation of glycoprotein biosynthetic process; IMP:RGD.
 GO:0032092; P:positive regulation of protein binding; IEA:Compara.
 GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:RGD.
 GO:0001934; P:positive regulation of protein phosphorylation; IMP:RGD.
 GO:0050714; P:positive regulation of protein secretion; IMP:RGD.
 GO:0045862; P:positive regulation of proteolysis; IMP:RGD.
 GO:0060298; P:positive regulation of sarcomere organization; IMP:RGD.
 GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:RGD.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.
 GO:0045727; P:positive regulation of translation; IMP:RGD.
 GO:0043491; P:protein kinase B signaling cascade; IDA:RGD.
 GO:0065004; P:protein-DNA complex assembly; IDA:RGD.
 GO:0060765; P:regulation of androgen receptor signaling pathway; IEA:Compara.
 GO:0060177; P:regulation of angiotensin metabolic process; IDA:RGD.
 GO:0051592; P:response to calcium ion; IMP:RGD.
 GO:0032025; P:response to cobalt ion; IEP:RGD.
 GO:0042493; P:response to drug; IMP:RGD.
 GO:0043627; P:response to estrogen stimulus; IEP:RGD.
 GO:0045471; P:response to ethanol; IEP:RGD.
 GO:0070542; P:response to fatty acid; IEP:RGD.
 GO:0051384; P:response to glucocorticoid stimulus; IMP:RGD.
 GO:0009749; P:response to glucose stimulus; IMP:RGD.
 GO:0001666; P:response to hypoxia; IEP:RGD.
 GO:0032526; P:response to retinoic acid; IEP:RGD.
 GO:0034612; P:response to tumor necrosis factor; IEP:RGD.
 GO:0007519; P:skeletal muscle tissue development; IEA:Compara.
 GO:0001756; P:somitogenesis; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS