| Tag | Content |
|---|
| CPLM ID | CPLM-023407 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Putative elongator complex protein 4 |
Protein Synonyms/Alias | ELP4 |
Gene Name | CG6907 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 399 | AFKLRRKKFIIEKFH | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation (By similarity). |
Sequence Annotation | MOD_RES 183 183 Phosphoserine.
MOD_RES 242 242 Phosphoserine. |
Keyword | Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 437 AA |
Protein Sequence | MTSFRKRTVQ KPIRGTRTSP HTAQVITSSG NPYLDVVIGG GLPMGSICLI EEDRFMTHAK 60
VLAKYFLAEG VISKQEIFLG SLDDIPAEML RRLPRPLTDQ ESMEQSEVQA LGDAGAENGL 120
RIAWRYNDLP LVNSEHATAK IGHHFNLMEQ MDSMMLYNVK TTLWDDSPKH LDIVIDEEFS 180
KSSSPTTPSL EQQPVEDAPP IPGTETAPQE KMPAQEEENS ANNNNNNNNN SSSVTSSTKT 240
GSQDSPLQVF HNPRYKGLLN DIQQLLRNES FVAGTKNNLC RVCLTSLGSP LWYDEHFGED 300
LIKFLTLLMA SVRNCNSVCL ITMPMHLIAK YDASLVPKIR QLVDYAIELE SFAGSERETH 360
PAFKEYSGLL HLHKMSAINT LAVHMPETPD LAFKLRRKKF IIEKFHLPPE LQESSAKPDN 420
CISGLLSNSN ATASLDF 437 |
Gene Ontology | GO:0005737; C:cytoplasm; ISS:UniProtKB. GO:0033588; C:Elongator holoenzyme complex; IEA:InterPro. GO:0008023; C:transcription elongation factor complex; ISS:UniProtKB. GO:0008607; F:phosphorylase kinase regulator activity; ISS:UniProtKB. GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |