UniProt Accession

 CRL_SALTY; Q7CR52 

Genbank Protein ID

 AE006468 

Genbank Nucleotide ID

 AAL19275.1 

Protein Name

 Sigma factor-binding protein Crl 

Protein Synonyms/Alias

  

Gene Name

 crl 

Gene Synonyms/Alias

 STM0319 

Created Date

 July 27, 2013 

Organism

 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 

NCBI Taxa ID

 99287 

Lysine Modification

Position	Peptide	Type	References
15	PKSRLIKKFTALGPY	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes, such as the csgBAC operon encoding the subunits of curli proteins, and BcsA, involved in cellulose biosynthesis. 

Sequence Annotation

 REGION 99 122 Essential for activity (By similarity).  

Keyword

 Activator; Coiled coil; Complete proteome; Cytoplasm; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 133 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016987; F:sigma factor activity; IEA:HAMAP.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR009986; Tscrpt_reg_Crl. 

Pfam

 PF07417; Crl 

SMART

  

PROSITE

  

PRINTS