CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042821
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Pumilio homolog 1 
Protein Synonyms/Alias
  
Gene Name
 PUM1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
168EQLLPGKKFWETDESubiquitination[1]
177WETDESSKDGPKGIFubiquitination[1, 2]
181ESSKDGPKGIFLGDQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1125 AA 
Protein Sequence
XQSPVGRHVV GVKGVGGMSV ACVLKRKAVL WQDSFSPHLK HHPQEPANPN MPVVLTSGTG 60
SQAQPQPAAN QALAAGTHSS PVPGSIGVAG RSQDDAMVDY FFQRQHGEQL GGGGSGGGGY 120
NNSKHRWPTG DNIHAEHQVR SMDELNHDFQ ALALEGRAMG EQLLPGKKFW ETDESSKDGP 180
KGIFLGDQWR DSAWGTSDHS VSQPIMVQRR PGQSFHVNSE VNSVLSPRSE SGGLGVSMVE 240
YVLSSSPGDS CLRKGGFGPR DADSDENDKG EKKNKGTFDG DKLGDLKEEG DVMDKTNGLP 300
VQNGIDADVK DFSRTPGNCQ NSANEVDLLG PNQNGSEGLA QLTSTNGAKP VEDFSNMESQ 360
SVPLDPMEHV GMEPLQFDYS GTQVPVDSAA ATVGLFDYNS QQQLFQRPNA LAVQQLTAAQ 420
QQQYALAAAH QPHIAGLAPA AFVPNPYIIS AAPPGTDPYT AGLAAAATLG PAVVPHQYYG 480
VTPWGVYPAS LFQQQAAAAA AATNSANQQT TPQAQQGQQQ VLRGGASQRP LTPNQNQQGQ 540
QTDPLVAAAA VNSALAFGQG LAAGMPGYPV LAPAAYYDQT GALVVNAGAR NGLGAPVRLV 600
APAPVIISSS AAQAAVAAAA ASANGAAGGL AGTTNGPFRP LGTQQPQPQP QQQPNNNLAS 660
SSFYGNNSLN SNSQSSSLFS QGSAQPANTS LGFGSSSSLG ATLGSALGGF GTAGGLTNGS 720
GRYISAAPGA EAKYRSASSA SSLFSPSSTL FSSSRLRYGM SDVMPSGRSR LLEDFRNNRY 780
PNLQLREIAG HIMEFSQDQH GSRFIQLKLE RATPAERQLV FNEILQAAYQ LMVDVFGNYV 840
IQKFFEFGSL EQKLALAERI RGHVLSLALQ MYGCRVIQKA LEFIPSDQQN EMVRELDGHV 900
LKCVKDQNGN HVVQKCIECV QPQSLQFIID AFKGQVFALS THPYGCRVIQ RILEHCLPDQ 960
TLPILEELHQ HTEQLVQDQY GNYVIQHVLE HGRPEDKSKI VAEIRGNVLV LSQHKFASNV 1020
VEKCVTHASR TERAVLIDEV CTMNDGPHSA LYTMMKDQYA NYVVQKMIDV AEPGQRKIVM 1080
HKIRPHIATL RKYTYGKHIL AKLEKYYMKN GVDLGPICGP PNGII 1125 
Gene Ontology
 GO:0003723; F:RNA binding; IEA:InterPro. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR001313; Pumilio_RNA-bd_rpt. 
Pfam
 PF00806; PUF 
SMART
 SM00025; Pumilio 
PROSITE
 PS50302; PUM
 PS50303; PUM_HD 
PRINTS