CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042005
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GTPase IMAP family member 4 
Protein Synonyms/Alias
 GTPase, IMAP family member 4, isoform CRA_a 
Gene Name
 GIMAP4 
Gene Synonyms/Alias
 hCG_1643312 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
52LRIVLVGKTGAGKSAubiquitination[1]
57VGKTGAGKSATGNSIubiquitination[1]
206RYCALNNKATGAEQEubiquitination[1, 2]
231QRVVRENKEGCYTNRubiquitination[1, 2]
249RAEEEIQKQTQAMQEubiquitination[1]
276IREEYEEKIRKLEDKacetylation[2]
276IREEYEEKIRKLEDKubiquitination[1]
296RKKQMEKKLAEQEAHubiquitination[1, 2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 343 AA 
Protein Sequence
MAAQYGSMSF NPSTPGASYG ERAFSAPQTR LQGGPGRQEP RNSQLRIVLV GKTGAGKSAT 60
GNSILGRKVF HSGTAAKSIT KKCEKRSSSW KETELVVVDT PGIFDTEVPN AETSKEIIRC 120
ILLTSPGPHA LLLVVPLGRY TEEEHKATEK ILKMFGERAR SFMILIFTRK DDLGDTNLHD 180
YLREAPEDIQ DLMDIFGDRY CALNNKATGA EQEAQRAQLL GLIQRVVREN KEGCYTNRMY 240
QRAEEEIQKQ TQAMQELHRV ELEREKARIR EEYEEKIRKL EDKVEQEKRK KQMEKKLAEQ 300
EAHYAVRQQR ARTEVESKDG ILELIMTALQ IASFILLRLF AED 343 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0005525; F:GTP binding; IEA:InterPro. 
Interpro
 IPR006703; AIG1.
 IPR027417; P-loop_NTPase. 
Pfam
 PF04548; AIG1 
SMART
  
PROSITE
  
PRINTS