UniProt Accession

 PSD13_RAT; B0BN93 

Genbank Protein ID

 CH473953; BC158732 

Genbank Nucleotide ID

 EDM11946.1; AAI58733.1 

Protein Name

 26S proteasome non-ATPase regulatory subunit 13 

Protein Synonyms/Alias

 26S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5 

Gene Name

 Psmd13 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
122	KTAIGALKLNIGDLQ	ubiquitination	[1]
161	RFYDLSSKYYQTIGN	ubiquitination	[1, 2]
186	FLGCVDIKDLPVSEQ	ubiquitination	[2]
298	LTFEEIAKSAKITVN	acetylation	[3]
329	GSIDEVDKRVHMTWV	acetylation	[3]
347	VLDLQQIKGMKDRLE	acetylation	[3]

Reference

 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). 

Sequence Annotation

 DOMAIN 231 335 PCI.
 MOD_RES 298 298 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; Proteasome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 376 AA 

Protein Sequence

Gene Ontology

 GO:0022624; C:proteasome accessory complex; ISS:UniProtKB.
 GO:0005838; C:proteasome regulatory particle; IEA:Compara.
 GO:0007127; P:meiosis I; IEA:Compara. 

Interpro

 IPR000717; PCI_dom. 

Pfam

 PF01399; PCI 

SMART

 SM00088; PINT 

PROSITE

  

PRINTS