UniProt Accession

 H3BLT4_HUMAN; H3BLT4 

Genbank Protein ID

 AC087645 

Genbank Nucleotide ID

  

Protein Name

 Baculoviral IAP repeat-containing protein 5 

Protein Synonyms/Alias

  

Gene Name

 BIRC5 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
15	PAWQPFLKDHRISTF	ubiquitination	[1]
23	DHRISTFKNWPFLEG	ubiquitination	[1, 2]
113	GCAFLSVKKQFEELT	ubiquitination	[2]
114	CAFLSVKKQFEELTL	ubiquitination	[1]
126	LTLGEFLKLDRERAK	ubiquitination	[2]
153	EFEETAEKVRRAIEQ	ubiquitination	[1, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 165 AA 

Protein Sequence

Gene Ontology

 GO:0009790; P:embryo development; IEA:Compara.
 GO:0000226; P:microtubule cytoskeleton organization; IEA:Compara.
 GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Compara. 

Interpro

 IPR001370; BIR. 

Pfam

 PF00653; BIR 

SMART

 SM00238; BIR 

PROSITE

 PS50143; BIR_REPEAT_2 

PRINTS