CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037685
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Condensin-2 complex subunit D3 
Protein Synonyms/Alias
  
Gene Name
 NCAPD3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
148DKCIQTLKKSWPQESubiquitination[1]
149KCIQTLKKSWPQESNubiquitination[1, 2, 3]
367ICAKVVDKSEYRTFAubiquitination[3]
442HQKFLKHKFLVQEIMubiquitination[1]
456MFDRCLDKAPTVRSKubiquitination[1, 3]
559DEKTNVRKSALQVLVubiquitination[1]
578HCDVSGMKEDLWILQubiquitination[1]
597DPAVSVRKQALQSLTubiquitination[1, 3]
618PRCVQIQKAWLRGVVubiquitination[1, 2]
687ELSRYLNKAFHIWSKubiquitination[1]
724PAWMLLSKIAGSSPRubiquitination[1]
743RIIQSWEKISSQQNPubiquitination[1]
776LPKSTRDKVTDAVKCubiquitination[1, 3]
782DKVTDAVKCKLNGFQubiquitination[1, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 832 AA 
Protein Sequence
MVALRGLGSG LQPWCPLDLR LEWVDTVWEL DFTETEPLDP SIEAEIIETG LAAFTKLYES 60
LLPFATGEHG SMESIWTFFI ENNVSHSTLV ALFYHFVQIV HKKNVSVQYR EYGLHAAGLY 120
FLLLEVPGSV ANQVFHPVMF DKCIQTLKKS WPQESNLNRK RKKEQPKSSQ ANPGRHRKRG 180
KPPRREDIEM DEIIEEQEDE NICFSARDLS QIRNAIFHLL KNFLRLLPKF SLKEKPQCVQ 240
NCIEVFVSLT NFEPVLHECH VTQARALNQA KYIPELAYYG LYLLCSPIHG EGDKVISCVF 300
HQMLSVILML EVGEGSHRAP LAVTSQVINC RNQAVQFISA LVDELKESIF PVVRILLQHI 360
CAKVVDKSEY RTFAAQSLVQ LLSKLPCGEY AMFIAWLYKY SRSSKIPHRV FTLDVVLALL 420
ELPEREVDNT LSLEHQKFLK HKFLVQEIMF DRCLDKAPTV RSKALSSFAH CLELTVTSAS 480
ESILELLINS PTFSVIESHP GTLLRNSSAF SYQRQTSNRS EPSGEINIDS SGETVGSGER 540
CVMAMLRRRI RDEKTNVRKS ALQVLVSILK HCDVSGMKED LWILQDQCRD PAVSVRKQAL 600
QSLTELLMAQ PRCVQIQKAW LRGVVPVVMD CESTVQEKAL EFLDQLLLQN IRHHSHFHSG 660
DDSQVLAWAL LTLLTTESQE LSRYLNKAFH IWSKKEKFSP TFINNVISHT GTEHSAPAWM 720
LLSKIAGSSP RLDYSRIIQS WEKISSQQNP NSNTLGHILC VIGHIAKHLP KSTRDKVTDA 780
VKCKLNGFQW SLEVISSAVD ALQRLCRASA ETPAEEQHWL EKESCVQRAV RA 832 
Gene Ontology
 GO:0007076; P:mitotic chromosome condensation; IEA:InterPro. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR026971; CND1/NCAPD3.
 IPR026003; Cohesin_HEAT. 
Pfam
 PF12765; Cohesin_HEAT 
SMART
  
PROSITE
  
PRINTS