CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013572
UniProt Accession
Genbank Protein ID
  
Genbank Nucleotide ID
  
Protein Name
 Protocadherin beta-7 
Protein Synonyms/Alias
 PCDH-beta-7 
Gene Name
 PCDHB7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Pan troglodytes (Chimpanzee) 
NCBI Taxa ID
 9598 
Lysine Modification
Position
Peptide
Type
References
766TNEFKFLKPIIPNLLubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965
Functional Description
 Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. 
Sequence Annotation
 DOMAIN 35 133 Cadherin 1.
 DOMAIN 138 242 Cadherin 2.
 DOMAIN 247 347 Cadherin 3.
 DOMAIN 352 451 Cadherin 4.
 DOMAIN 456 561 Cadherin 5.
 DOMAIN 568 671 Cadherin 6.
 CARBOHYD 169 169 N-linked (GlcNAc...) (Potential).
 CARBOHYD 418 418 N-linked (GlcNAc...) (Potential).
 CARBOHYD 436 436 N-linked (GlcNAc...) (Potential).
 CARBOHYD 567 567 N-linked (GlcNAc...) (Potential).  
Keyword
 Calcium; Cell adhesion; Cell membrane; Complete proteome; Glycoprotein; Membrane; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 793 AA 
Protein Sequence
MEARVERAVQ KRQVLFLCVF LGMSWAGAEP LRYFVAEETE RGTFLTNLAK DLGLGVGELR 60
ARGTRIVSDQ NMQILLLSSL TGDLLLNEKL DREELCGPRE PCVLPFQLLL EKPFQIFRAE 120
LWVRDINDHA PVFLDREISL KILESTTPGA AFLLESAQDS DVGTNSLSNY TISPNAYFHI 180
NVHDSGEGNI YPELVLNQVL DREEIPEFSL TLTALDGGSP PRSGTALVRI LVLDVNDNAP 240
DFVRSLYKVQ VPENSPVGSM VVSVSARDLD TGSNGEIAYA FSYATERILK TFQINPTSGN 300
LHLKAQLDYE AIQTYTLTIQ AKDGGGLSGK CTVVVDVTDI NDNRPELLLS SLTSPIAENS 360
PETVVAVFRI RDRDSGNNGK TVCSIQDDLP FILKPSVENF YTLVSEKPLD RERNTEYNIT 420
ITVTDLGTPR LKTEHNITVL VSDVNDNAPA FTQTSYTLFV RENNSPALPI GSVSATDRDS 480
GTNAQVIYSL LPSQDPHLPL SSLVSINADN GHLFALRSLD YEALQAFEFR VGATDRSSPA 540
LSSEALVHVL VLDANDNSPF VLYPLQNSSA PCTEPLPRAA EPGYLVTKVV AVDGDSGQNA 600
WLSYQLLKAT EPGLFGVWAH NGEVRTARLL SERDAAKQRL VVLVKDNGEP PRSATATLHV 660
LLVDGFSQPY LRLPEAAPDQ ANLLTVYLVV ALASVSSLFL LSVLLFVAVR LCRRSRAAPV 720
GRCSVPEGPF PRHLVDLSGT GTLSQSYQYE VCLTGGSGTN EFKFLKPIIP NLLPQSTGRE 780
VEENRPFQNN LGF 793 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0007156; P:homophilic cell adhesion; IEA:InterPro. 
Interpro
 IPR002126; Cadherin.
 IPR015919; Cadherin-like.
 IPR020894; Cadherin_CS.
 IPR013164; Cadherin_N. 
Pfam
 PF00028; Cadherin
 PF08266; Cadherin_2 
SMART
 SM00112; CA 
PROSITE
 PS00232; CADHERIN_1
 PS50268; CADHERIN_2 
PRINTS
 PR00205; CADHERIN.