CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040044
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ankyrin repeat and SAM domain-containing protein 6 
Protein Synonyms/Alias
  
Gene Name
 ANKS6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
52VAQQLVEKGANPDHLubiquitination[1]
74FEVALDCKHRDLVDYubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 676 AA 
Protein Sequence
MAAIQHGHEA VVRLLMEWGA DPNHAARTVG WSPLMLAALT GRLGVAQQLV EKGANPDHLS 60
VLEKTAFEVA LDCKHRDLVD YLDPLTTVRP KTDEEKRRPD IFHALKMGNF QLVKEIADED 120
PSHVNLVNGD GATPLMLAAV TGQLALVQLL VERHADVDKQ DSVHGWTALM QATYHGNKEI 180
VKYLLNQGAD VTLRAKNGYT AFDLVMLLND PDTELVRLLA SVCMQVNKDK GRPSHQPPLP 240
HSKVRQPWSI PVLPDDKGGL KSWWNRMSNR FRKLKLMQTL PRGLSSNQPL PFSDEPEPAL 300
DSTMRAAPQD KTSRSALPDA APVTKDNGPG STRGEKEDTL LTTMLRNGAP LTRLPSDKLK 360
AVIPPFLPPS SFELWSSDRS RTRHNGKADP MKTALPQRAS RGHPVGGGGT DTTPVRPVKF 420
PSLPRSPASS ANSGNFNHSP HSSGGSSGVG VSRHGGELLN RSGGSIDNVL SQIAAQRKKA 480
AGLLEQKPSH RSSPVGPAPG SSPSELPASP AGGSAPVGKK LETSKRPPSG TSTTSKSTSP 540
TLTPSPSPKG HTAESSVSSS SSHRQSKSSG GSSSGTITDE DELTGILKKL SLEKYQPIFE 600
EQEVDMEAFL TLTDGDLKEL GIKTDGSRQQ ILAAISELNA GKGRERQILQ ETIHNFHSSF 660
ESSASNTRAP GNSPCA 676 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR001660; SAM.
 IPR013761; SAM/pointed.
 IPR021129; SAM_type1. 
Pfam
 PF12796; Ank_2
 PF00536; SAM_1 
SMART
 SM00248; ANK
 SM00454; SAM 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50105; SAM_DOMAIN 
PRINTS
 PR01415; ANKYRIN.