CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018560
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 
Protein Synonyms/Alias
 Alpha 2,3-ST 4; Beta-galactoside alpha-2,3-sialyltransferase 4; Alpha 2,3-sialyltransferase IV; Gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase; ST3Gal IV; ST3GalIV; Sialyltransferase 4C; SIAT4-C 
Gene Name
 St3gal4 
Gene Synonyms/Alias
 Siat4c 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
91YELPFGTKGSEDLLLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 It may catalyze the formation of the NeuAc-alpha-2,3- Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids (By similarity). 
Sequence Annotation
 CARBOHYD 61 61 N-linked (GlcNAc...) (Potential).
 CARBOHYD 131 131 N-linked (GlcNAc...) (Potential).
 CARBOHYD 310 310 N-linked (GlcNAc...) (Potential).
 CARBOHYD 329 329 N-linked (GlcNAc...) (Potential).
 DISULFID 120 273 By similarity.  
Keyword
 Complete proteome; Disulfide bond; Glycoprotein; Glycosyltransferase; Golgi apparatus; Membrane; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 333 AA 
Protein Sequence
MTSKSHWKLL ALALVLVVVM VWYSISREDR YIEFFYFPIS EKKEPCFQGE AERQASKIFG 60
NRSREQPIFL QLKDYFWVKT PSTYELPFGT KGSEDLLLRV LAITSYSIPE SIKSLECRRC 120
VVVGNGHRLR NSSLGGVINK YDVVIRLNNA PVAGYEGDVG SKTTIRLFYP ESAHFDPKIE 180
NNPDTLLVLV AFKAMDFHWI ETILSDKKRV RKGFWKQPPL IWDVNPKQVR ILNPFFMEIA 240
ADKLLSLPIQ QPRKIKQKPT TGLLAITLAL HLCDLVHIAG FGYPDASNKK QTIHYYEQIT 300
LKSMAGSGHN VSQEAIAIKR MLEMGAVKNL TYF 333 
Gene Ontology
 GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
 GO:0030173; C:integral to Golgi membrane; IEA:InterPro.
 GO:0003836; F:beta-galactoside (CMP) alpha-2,3-sialyltransferase activity; IDA:MGI.
 GO:0047288; F:monosialoganglioside sialyltransferase activity; IEA:Compara.
 GO:0006486; P:protein glycosylation; IDA:MGI. 
Interpro
 IPR001675; Glyco_trans_29.
 IPR012163; Sialyl_trans. 
Pfam
 PF00777; Glyco_transf_29 
SMART
  
PROSITE
  
PRINTS