| Tag | Content |
|---|
| CPLM ID | CPLM-016881 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vacuolar protein sorting-associated protein 37A |
Protein Synonyms/Alias | Vps37A; ESCRT-I complex subunit VPS37A |
Gene Name | Vps37a |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 29 | LTSLQQQKQRLIESL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation (By similarity). |
Sequence Annotation | DOMAIN 308 397 VPS37 C-terminal.
MOD_RES 18 18 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Endosome; Membrane; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 397 AA |
Protein Sequence | MSWLFPLAKS ASSSAAGSPA GLTSLQQQKQ RLIESLRNSH SSIAEIQKDV EYRLPFTVNN 60
LTININILLP PQFPQEKPVI SVYPPIRHHL MDSQGLYVTS PLVSNFTMHS DLGKIIQSLL 120
DEFWKNPPVL APTSTTFPYL YSNPGGMPPY PSQGFPFLPP YPPPEANRNI TSLSVADTVS 180
SSTTSYTAAK PVAPSFGILS SLPLPVPTTE SSASVNQNGF GYKMPDIPDA FPELSELSVS 240
QLTDMNEQEE VLLEQFLMLP QLKQIITDKE DLVKNIEELA RKNLLLEHSL EGKRQTVLDK 300
YELLLQMKST FEKKMQRQHE LSESCSASAL QARLKVAAHE AEEESDNIAE DFLEGKTEID 360
DFLNSFKEKR TICHCRRAKE EKLHQVIAMH SQFHAPL 397 |
Gene Ontology | GO:0005813; C:centrosome; IEA:Compara. GO:0000813; C:ESCRT I complex; ISS:UniProtKB. GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0015031; P:protein transport; IEA:UniProtKB-KW. GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |