CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016279
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Coiled-coil domain-containing protein 25 
Protein Synonyms/Alias
  
Gene Name
 CCDC25 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
23TIYMGKDKYENEDLIacetylation[1]
100TPWSNLKKTADMDVGubiquitination[2]
Reference
 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 MOD_RES 23 23 N6-acetyllysine.
 MOD_RES 187 187 Phosphoserine (By similarity).
 MOD_RES 204 204 Phosphoserine.  
Keyword
 Acetylation; Coiled coil; Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 208 AA 
Protein Sequence
MVFYFTSSSV NSSAYTIYMG KDKYENEDLI KHGWPEDIWF HVDKLSSAHV YLRLHKGENI 60
EDIPKEVLMD CAHLVKANSI QGCKMNNVNV VYTPWSNLKK TADMDVGQIG FHRQKDVKIV 120
TVEKKVNEIL NRLEKTKVER FPDLAAEKEC RDREERNEKK AQIQEMKKRE KEEMKKKREM 180
DELRSYSSLM KVENMSSNQD GNDSDEFM 208 
Gene Ontology
  
Interpro
 IPR008532; DUF814. 
Pfam
 PF05670; DUF814 
SMART
  
PROSITE
  
PRINTS