CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004830
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Meiosis-specific protein HOP1 
Protein Synonyms/Alias
  
Gene Name
 HOP1 
Gene Synonyms/Alias
 YIL072W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
58DQRFVPEKVEKNYNKacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Probable constituent of the synaptonemal complex during meiosis. May interact with RED1. 
Sequence Annotation
 DOMAIN 20 250 HORMA.
 ZN_FING 348 364  
Keyword
 Chromosome; Complete proteome; DNA-binding; Meiosis; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 605 AA 
Protein Sequence
MSNKQLVKPK TETKTEITTE QSQKLLQTML TMSFGCLAFL RGLFPDDIFV DQRFVPEKVE 60
KNYNKQNTSQ NNSIKIKTLI RGKSAQADLL LDWLEKGVFK SIRLKCLKAL SLGIFLEDPT 120
DLLENYIFSF DYDEENNVNI NVNLSGNKKG SKNADPENET ISLLDSRRMV QQLMRRFIII 180
TQSLEPLPQK KFLTMRLMFN DNVDEDYQPE LFKDATFDKR ATLKVPTNLD NDAIDVGTLN 240
TKHHKVALSV LSAATSSMEK AGNTNFIRVD PFDLILQQQE ENKLEESVPT KPQNFVTSQT 300
TNVLGNLLNS SQASIQPTQF VSNNPVTGIC SCECGLEVPK AATVLKTCKS CRKTLHGICY 360
GNFLHSSIEK CFTCIFGPSL DTKWSKFQDL MMIRKVFRFL VRKKKGFPAS ITELIDSFIN 420
VEDQNNEVKE RVAFALFVFF LDETLCLDNG GKPSQTIRYV TSSVLVDVKG IVIPNTRKQL 480
NVNHEYKWHF TTSSPKAESF YQEVLPNSRK QVESWLQDIT NLRKVYSEAL SPSSTLQELD 540
LNSSLPTQDP IISGQKRRRY DLDEYLEEDK SSVVNDTIKA KDFDESVPAK IRKISVSKKT 600
LKSNW 605 
Gene Ontology
 GO:0000800; C:lateral element; IPI:SGD.
 GO:0000400; F:four-way junction DNA binding; IDA:SGD.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0051598; P:meiotic recombination checkpoint; IGI:SGD.
 GO:0007130; P:synaptonemal complex assembly; IMP:SGD. 
Interpro
 IPR016573; HOP1_fun.
 IPR003511; HORMA_DNA-bd. 
Pfam
 PF02301; HORMA 
SMART
  
PROSITE
 PS50815; HORMA 
PRINTS