CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017905
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial 
Protein Synonyms/Alias
 MCT; Bad egg; [Acyl-carrier-protein] malonyltransferase 
Gene Name
 beg 
Gene Synonyms/Alias
 CG7842 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
309VYSNVDGKPYRHAKHacetylation[1]
323HILTQLPKQIVRPVKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Catalyzes the transfer of a malonyl moiety from malonyl- CoA to the free thiol group of the phosphopantetheine arm of the ACP protein. This suggests the existence of the biosynthesis of fatty acids in mitochondrias (By similarity). 
Sequence Annotation
 ACT_SITE 158 158 By similarity.
 ACT_SITE 275 275 By similarity.  
Keyword
 Complete proteome; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; Mitochondrion; Reference proteome; Transferase; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 379 AA 
Protein Sequence
MLAARRLLRS PRITGALSWS RWSSDAAKAT TETSALLQNA EKRQQLLNEL SEPLEQKGRP 60
AIDPKETSVM LFPGQGTQYV GMAKDLLRFP GARRIFELAN EVLKYDLLKI CLEGPREKLN 120
RTEHAQLAVM VSSLAALEQL REERPKAIET CVAAAGFSLG EITALVYADA LPFDKALRLV 180
QVRATAMQAA CDQAAGAMAM TLYGPDTNLG EACARAQQWC LDKGVESPYC GIANYMYPHC 240
KVVAGNVEAL EFLEQNAKSF KIRRMKRLAV SGAFHTPLMQ SAVEPFTKAL KTVRLQDPVI 300
RVYSNVDGKP YRHAKHILTQ LPKQIVRPVK WEQTLHEMYE RKQGVDFPRT FECGPGKGLV 360
QVLEKVNAKA AQSSFNVIA 379 
Gene Ontology
 GO:0005739; C:mitochondrion; ISS:UniProtKB.
 GO:0004314; F:[acyl-carrier-protein] S-malonyltransferase activity; ISS:UniProtKB.
 GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB. 
Interpro
 IPR001227; Ac_transferase_dom.
 IPR014043; Acyl_transferase.
 IPR016035; Acyl_Trfase/lysoPLipase.
 IPR016036; Malonyl_transacylase_ACP-bd. 
Pfam
 PF00698; Acyl_transf_1 
SMART
  
PROSITE
  
PRINTS