UniProt Accession

 RME1_YEAST; P32338; D6VUI2; Q45TA6 

Genbank Protein ID

 M76447; DQ116799; DQ116801; DQ116802; DQ116804; DQ116805; DQ116806; DQ116807; Z72829; BK006941 

Genbank Nucleotide ID

 AAA35238.1; AAZ29879.1; AAZ29881.1; AAZ29882.1; AAZ29884.1; AAZ29885.1; AAZ29886.1; AAZ29887.1; CAA97043.1; DAA08143.1 

Protein Name

 Zinc finger protein RME1 

Protein Synonyms/Alias

  

Gene Name

 RME1 

Gene Synonyms/Alias

 YGR044C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
174	TISEGQTKRGSYHCS	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Involved in the control of meiosis. Represses the transcription of the IME1 gene thereby inhibiting cells from entering meiosis. But also activates the CLN2 gene thus promoting mitosis. 

Sequence Annotation

 ZN_FING 178 199 C2H2-type 1.
 ZN_FING 206 234 C2H2-type 2.
 ZN_FING 256 281 C2H2-type 3.  

Keyword

 Activator; Cell cycle; Cell division; Complete proteome; DNA-binding; Meiosis; Metal-binding; Mitosis; Nucleus; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 300 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.
 GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IMP:SGD.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW.
 GO:0045835; P:negative regulation of meiosis; IMP:SGD.
 GO:0051038; P:negative regulation of transcription during meiosis; IMP:SGD.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:SGD.
 GO:0036095; P:positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.
 GO:0071931; P:positive regulation of transcription involved in G1/S phase of mitotic cell cycle; IDA:SGD. 

Interpro

 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like. 

Pfam

  

SMART

 SM00355; ZnF_C2H2 

PROSITE

 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 

PRINTS