UniProt Accession

 RRAS_MOUSE; P10833 

Genbank Protein ID

 M21019; BC009105 

Genbank Nucleotide ID

 AAA40038.1; AAH09105.1 

Protein Name

 Ras-related protein R-Ras 

Protein Synonyms/Alias

 p23 

Gene Name

 Rras 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
192	QLVRAVRKYQEQELP	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Regulates the organization of the actin cytoskeleton (By similarity). 

Sequence Annotation

 NP_BIND 36 44 GTP (By similarity).
 NP_BIND 83 87 GTP (By similarity).
 NP_BIND 142 145 GTP (By similarity).
 NP_BIND 172 174 GTP (By similarity).
 MOTIF 58 66 Effector region (By similarity).
 MOD_RES 215 215 Cysteine methyl ester (By similarity).
 LIPID 215 215 S-geranylgeranyl cysteine (By  

Keyword

 Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Prenylation; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 218 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0019003; F:GDP binding; ISS:UniProtKB.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; ISS:UniProtKB.
 GO:0030336; P:negative regulation of cell migration; IGI:MGI.
 GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR020849; Small_GTPase_Ras. 

Pfam

 PF00071; Ras 

SMART

 SM00173; RAS 

PROSITE

 PS51421; RAS 

PRINTS

 PR00449; RASTRNSFRMNG.