CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010734
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog 
Protein Synonyms/Alias
  
Gene Name
 Arvcf 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
923STGDTSEKELLRPDPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Involved in protein-protein interactions at adherens junctions (By similarity). 
Sequence Annotation
 REPEAT 350 389 ARM 1.
 REPEAT 392 431 ARM 2.
 REPEAT 435 469 ARM 3.
 REPEAT 470 510 ARM 4.
 REPEAT 528 567 ARM 5.
 REPEAT 577 623 ARM 6.
 REPEAT 647 687 ARM 7.
 REPEAT 700 739 ARM 8.
 REPEAT 740 782 ARM 9.
 REPEAT 783 827 ARM 10.
 MOTIF 608 624 Nuclear localization signal (Potential).
 MOD_RES 269 269 Phosphoserine.
 MOD_RES 643 643 Phosphothreonine.
 MOD_RES 864 864 Phosphoserine (By similarity).
 MOD_RES 871 871 Phosphoserine (By similarity).
 MOD_RES 872 872 Phosphothreonine (By similarity).  
Keyword
 Alternative splicing; Cell adhesion; Coiled coil; Complete proteome; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 962 AA 
Protein Sequence
MEDCNVHSAA SILASVKEQE ARFERLTRAL EQERRHVALQ LERAQQPGMS SGGMVGSGQP 60
LPMAWQQLVL QEQSPGSQAS LATMPEAPEV LEETVTVEED PGTPTSHVSI VTSEDGTTRR 120
TETKVTKTVK TVTTRTVRQV PLGPDGLPLL DGGPPLGSFA DGPLDRHYLL RGGGGPAATL 180
SRTYHSSGGG FPDGPESRDI PSYGSLSRGL GVRPPRTGLL GPGPGDGCFT LPGRREAFPM 240
GSESGPPSGR SLPEHFQAEP YGLEDDTRSL AADDEGGPDL EPDYSTATRR RPEYGRGLRA 300
RAFEDTADDA GELIEERPPF PAATAPLAQP ERGSLGSLDR VVRRSPSVDS TRKEPRWRDP 360
ELPEVLAMLR HPVDPVKANA AAYLQHLCFE NEGIKRRVRQ LRGLPLLVAL LDHPRAEVRR 420
RACGALRNLS YGRDTDNKAA IRDCGGVPAL VRLLRAARDN EVRELVTGTL WNLSSYEPLK 480
MVIIDHGLQT LTHEVIVPHS GWEREPNEDS KPRDAEWTTV FKNTSGCLRN VSSDGAEARR 540
RLRECEGLVD ALLHALQSAV GRKDTDNKSV ENCVCIMRNL SYHVHKEVPG ADRYQEAEPG 600
IPGSTTSQRR RKDDASCFGG KKAKEEWFHQ GKKDAEMDRN FDTLDLPKRT EAAKGFELLY 660
QPEVVRLYLS LLTESRNFNT LEAAAGALQN LSAGNWTWAT YIRATVRKER GLPVLVELLQ 720
SETDKVVRAV AIALRNLSLD QRNKDLIGSY AMTELVRNVR NAQAPAHPSA HLEEDTVVAV 780
LNTIHEIVSD SLDNARSLLQ ARGVPALVAL VASSQSVREA KAASHVLQTV WSYKELRGAL 840
QRDGWTKSRF QSASTAKGPK GTPSSGGFDD STLPLVDKSL DGEKSNTRDV IPMDTLGPDG 900
YATVDRRERR TLGSDSTGDT SEKELLRPDP GRKAPPPGPS RPSVRLVDAV GDTKPQPVDS 960
WV 962 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0005886; C:plasma membrane; IDA:MGI.
 GO:0016339; P:calcium-dependent cell-cell adhesion; TAS:MGI. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR000225; Armadillo. 
Pfam
 PF00514; Arm 
SMART
 SM00185; ARM 
PROSITE
 PS50176; ARM_REPEAT 
PRINTS