Tag | Content |
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CPLM ID | CPLM-035509 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein Herc1 |
Protein Synonyms/Alias | |
Gene Name | Herc1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
---|
1808 | KLRPNYDKTEIEKKG | ubiquitination | [1] | 2925 | GKTMVQGKNYGPQIT | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Ligase; Reference proteome; Repeat; Ubl conjugation pathway; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 3276 AA |
Protein Sequence | GPMHSQLESL SDSWTRLKHT RDWFYNSSYS FESDFDLTKS LGVHTLIENV VSFVSGDVGN 60 APGFKEPEES MSTSPQASII AMEQQQLRAE LRLEALHQIL TLLSGMEEKG NILLTGSRSS 120 SGFQSSTLLT SVRLQFLAGC FGLGTVGYTG AKGESGRLHH YQDGIRAAKR NIQVEIQVAV 180 HKIYQQLSAT LERALQANKH HIEAQQRLLL VTVFALSVHY QPAXXXXXXX TGLLNVLSQL 240 CGTDTMLGQP LQLLPKTGVS QLSTALKVAS TRLLQILAIT TGTYADKLSP KVVQSLLDLL 300 CSQLKNLLSQ TGVLFMASFG EGEEGEEEDK KVDSSGEAEK RDFRAALRKQ HAAELHLGDF 360 LVFLRRVVSS KAIQSKMASP KWTEVLLNIA SQKCSSGIPL VGNLRTRLLA LHVLEAVLPA 420 CESGVEDDQM AQVVERLFSL LSDCMWETPI AQAKHAIQIK EKEQEIKLQK QGELEEEDEN 480 LPIQEVSFDP EKAQCCIVEN GQILTHGSGG KGYGLASTGV TSGCYQWKFY IVKENRGNEG 540 TCVGVSRWPV HDFNHRTTSD MWLYRAYSGN LYHNGEQTLT LSSFTQGDFI TCVLDMEART 600 ISFGKNGEEP KLAFEDVDAA ELYPCVMFYS SNPGEKVKIC DMQMRGTPRD LLPGDPICSP 660 VAAVLAEATI QLIRILHRTD RWTYCINKKM MERLHKIKIC IRESGQKLKK SRSVQSREEN 720 EMREEKENKE EEKGKHNRHG LADLSEPQLR TLCIEVWPVL AVIGGVDAGL RVGGRCVHKQ 780 TGRHATLLGV VKEGSTSAKV QWDEAEITIS FPTFWSPSDT PLYNLEPCEP LLFDVARFRG 840 LTASVLLDLT YLTGIHEDIG KQSIKRHEKK HRHESEEKGD IEQKPESESI LDVRTGLISD 900 DVKSQGTTSS KSENEIASFS LESTLPGVES QHQITEGKRK NHEHISKTHD IAQSEIRAVQ 960 LSYLYLGAMK SLSALLGCSK YAELLLIPKV LAENGHNSDC ASSPVVHEDV EMRAALQFLM 1020 RHMVKRAVMR SPIKRALGLA DLERAQAMIY KLVVHGLLED QFGGKIKQEI DQQAEESDQA 1080 QQAQTPVTTS PSASSTTSFM SSSLEDTTTA TTPVTDTETV PASESPGVMP LSLLRQMFSS 1140 YPTTTVLPTR RAQTPPISSL PASPSDEVGR RQSLTSPDSQ STRPANRTAL SDPSSRLSTS 1200 PPPPAIAVPL LEMGFSLRQI AKAMEATGAR GEADAQNITV LAMWMIEHPG HEDEEEPQSS 1260 STADSRHGTA VLGSGGKSND PCYLQSPGDI PSADAAEMEE GFSESPDNLD HTENAASGSG 1320 PPTRGRSTVT RRHKFDLAAR TLLARAAGLY RSVQAHRNQS RREGISLQQD PGALYDFNLD 1380 EELEIDLDDE AMEAMFGQDL TSDNDILGMW IPEVLDWPTW HVCESEDREE VVVCELCECN 1440 VVSFNQHMKR NHPGCGRSAN RQGYRSNGSY VDGWFGGECG SGNPYYLLCG SCREKYLALK 1500 TKTKTTNSER YKGQAPDLIG KQDSVYEEDW DMLDVDEDEK LTGEEEFELL AGPLGLNDRR 1560 IVPEPVQFPD SDPLGASVAM VTATNSMEET LMQIGCHGSV EKSSSGRVTL GEQAAALANP 1620 HDRVVALRRV TAAAQVLLAR TMVMRALSLL SVSGSSCSLA AGLESLGLTD IRTLVRLMCL 1680 AAAGRAGLST SPSAIASTSE RSRGGHSKAS KPISCLAYLS TAVGCLASNT PSAAKLLVQL 1740 CTQNLISAAT GVNLTTVDDP IQRKFLPSFL RGIAEENKLV TSPNFVVTQA LVALLADKGA 1800 KLRPNYDKTE IEKKGPLELA NALAACCLSS RLSSQHRQWA AQQLVRTLAA HDRDNQTAPQ 1860 TLADMGGDLR KCSFIKLEAH QNRVMTCVWC NKKGLLATSG NDGTIRVWNV TKKQYSLQQT 1920 CVFNRLEGDA EESLGSPSDP SFSPVSWSIS GKYLAGALEK MVNIWQVNGG KGLVDIQPHW 1980 VSALAWPEEG PATAWSGESP ELLLVGRMDG SLGLIEVVDV STMHRRELEH CYRKDVSVTC 2040 IAWFSEDRPF AVGYFDGKLL MGTKEPLEKG GIVLIDAHKE TLVSMKWDPT GHILMTCAKE 2100 ENVKLWGPVS GCWRCLHSLC HPSTVNGIAW CSLPGKGSKM QLLMATGCQN GLVCVWCIPQ 2160 DTTQTSMTSS EGWWDQESNC QDGFKKSAGA KCVYQLRGHI TPVRTVAFSS DGLALVSGGL 2220 GGLMNIWSLR DGSVLQTVVI GSGAIQTTVW IPEVGVAACS NRSKDVLVVN CTAEWASANH 2280 ILATCRTALK QQGVLGLNMA PCMRAFLERL PMMLQEQYAY EKPHVVCGDQ LVHSPYMQCL 2340 ASLAVGLHLD QLLCSPPVPP HHQNCPPDPA SWNPNEWAWL ECFSTTIKAA EALTNGAQFP 2400 ESFTVPDLEP VPEDELVLLM DNSKWINGMD EQIMSWATSR PEDWHLGGKC DVYLWGAGRH 2460 GQLAEAGRNV MVPATAPSFS QAQQVICGQN CTFVIQANGT VLACGEGSYG RLGQGNSDDL 2520 HVLTVISALQ GFVVTQLVTS CGSDGHSMAL TESGEVFSWG DGDYGKLGHG NSDRQRRPRQ 2580 IEALQGEEVV QMSCGFKHSA VVTSDGKLFT FGNGDYGRLG LGNTSNKKLP ERVTALEGYQ 2640 IGQAWHKVAC GLNHTLAVSA DGSMVWAFGD GDYGKLGLGN STAKSSPQKV DVLCGIGIKK 2700 VACGTQFSVA LTKDGHVYTF GQDRLIGLPE GRARNHNRPQ QIPVLAGVVI EDVAVGAEHT 2760 LALASTGDVY AWGSNSEGQL GLGHTNHVRE PTLVTVLQGK NIRQISAGRC HSAAWTAPPV 2820 PPRAPGVSVP LQLGLPDAVP PQYGALREVS IHTVRARLRL LYHFSDLMYS SWRLLNLSPN 2880 NQNSTSHYNA GTWGIVQGQL RPLLAPRVYT LPMVRSIGKT MVQGKNYGPQ ITVKRISTRG 2940 RKCKPIFVQI ARQVVKLNAS DLRLPSRAWK VKLVGEGADD AGGVFDDTIT EMCQELETGI 3000 VDLLIPSPNA TAEVGYNRDR FLFSPSACLD EHLMQFKFLG ILMGVAIRTK KPLDLHLAPL 3060 VWKQLCCVPL TLEDLEEVDL LYVQTLNSIL HIEDSGITEE SFHEMIPLDS FVGQSADGKM 3120 VPIIPGGNSI PLTFSNRKEY VERAIEYRLH EMDRQVAAVR EGMSWIVPVP LLSLLTAKQL 3180 EQMVCGMPEI CVDVLKKVVR YREVDEQHQL VQWLWRTLEE FSNEERVLFM RFVSGRSRLP 3240 ANTADISQRF QIMKVDRPHA SPPSQALCLF HVRLPP 3276 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro. GO:0016567; P:protein ubiquitination; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |