UniProt Accession

 Q4VX54_HUMAN; Q4VX54; Q5STK8 

Genbank Protein ID

 AL662820 

Genbank Nucleotide ID

  

Protein Name

 Death domain-associated protein 6 

Protein Synonyms/Alias

  

Gene Name

 DAXX 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
60	SGGKKCYKLENEKLF	ubiquitination	[1]
65	CYKLENEKLFEEFLE	ubiquitination	[1, 2]
75	EEFLELCKMQTADHP	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 178 AA 

Protein Sequence

Gene Ontology

 GO:0000792; C:heterochromatin; IEA:Compara.
 GO:0016605; C:PML body; IEA:Compara.
 GO:0000281; P:mitotic cytokinesis; IEA:Compara.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara. 

Interpro

 IPR005012; Daxx. 

Pfam

 PF03344; Daxx 

SMART

  

PROSITE

  

PRINTS