CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015915
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein MON2 homolog 
Protein Synonyms/Alias
 Protein SF21 
Gene Name
 MON2 
Gene Synonyms/Alias
 KIAA1040; SF21 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
281RVCPLVIKLFSPNIKubiquitination[1, 2]
288KLFSPNIKFRQGSSTubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 May be required for traffic between late Golgi and early endosomes (By similarity). 
Sequence Annotation
 MOD_RES 205 205 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1718 AA 
Protein Sequence
MSGTSSPEAV KKLLENMQSD LRALSLECKK KFPPVKEAAE SGIIKVKTIA ARNTEILAAL 60
KENSSEVVQP FLMGCGTKEP KITQLCLAAI QRLMSHEVVS ETAAGNIINM LWQLMENSLE 120
ELKLLQTVLV LLTTNTVVHD EALSKAIVLC FRLHFTKDNI TNNTAAATVR QVVTVVFERM 180
VAEDERHRDI IEQPVLVQGN SNRRSVSTLK PCAKDAYMLF QDLCQLVNAD APYWLVGMTE 240
MTRTFGLELL ESVLNDFPQV FLQHQEFSFL LKERVCPLVI KLFSPNIKFR QGSSTSSSPA 300
PVEKPYFPIC MRLLRVVSVL IKQFYSLLVT ECEIFLSLLV KFLDADKPQW LRAVAVESIH 360
RFCVQPQLLR SFCQSYDMKQ HSTKVFRDIV NALGSFIQSL FLVPPTGNPA TSNQAGNNNL 420
GGSVSAPANS GMVGIGGGVT LLPAFEYRGT WIPILTITVQ GSAKATYLEM LDKVEPPTIP 480
EGYAMSVAFH CLLDLVRGIT SMIEGELGEL ETECQTTTEE GSSPTQSTEQ QDLQSTSDQM 540
DKEIVSRAVW EEMVNACWCG LLAALSLLLD ASTDEAATEN ILKAELTMAA LCGRLGLVTS 600
RDAFITAICK GSLPPHYALT VLNTTTAATL SNKSYSVQGQ SVMMISPSSE SHQQVVAVGQ 660
PLAVQPQGTV MLTSKNIQCM RTLLNLAHCH GAVLGTSWQL VLATLQHLVW ILGLKPSSGG 720
ALKPGRAVEG PSTVLTTAVM TDLPVISNIL SRLFESSQYL DDVSLHHLIN ALCSLSLEAM 780
DMAYGNNKEP SLFAVAKLLE TGLVNMHRIE ILWRPLTGHL LEKVCQHPNS RMREWGAEAL 840
TSLIKAGLTF NHDPPLSQNQ RLQLLLLNPL KEMSNINHPD IRLKQLECVL QILQSQGDSL 900
GPGWPLVLGV MGAIRNDQGE SLIRTAFQCL QLVVTDFLPT MPCTCLQIVV DVAGSFGLHN 960
QELNISLTSI GLLWNISDYF FQRGETIEKE LNKEEAAQQK QAEEKGVVLN RPFHPAPPFD 1020
CLWLCLYAKL GELCVDPRPA VRKSAGQTLF STIGAHGTLL QHSTWHTVIW KVLFHLLDRV 1080
RESSTTADKE KIESGGGNIL IHHSRDTAEK QWAETWVLTL AGVARIFNTR RYLLQPLGDF 1140
SRAWDVLLDH IQSAALSKNN EVSLAALKSF QEILQIVSPV RDSDKPETPP VVNVPVPVLI 1200
GPISGMSRPF VRTDSIGEKL GRYSSSEPPI VTDELEDLNL WWAAWNTWYR IGSESTKPPI 1260
TFDKLTFIPS QPFLTALIQI FPALYQHIKT GFNMDDLQKL GVILHSAISV PISSDASPFI 1320
LPSYTEAVLT SLQEAVLTAL DVLQKAICVG PENMQIMYPA IFDQLLAFVE FSCKPPQYGQ 1380
LETKHIANAK YNQIQLFAPA EWVALNYVPF AERSLEVVVD LYQKTACHKA VVNEKVLQNI 1440
IKTLRVPLSL KYSCPSESTW KLAVSSLLRV LSIGLPVARQ HASSGKFDSM WPELANTFED 1500
FLFTKSIPPD NLSIQEFQRN ENIDVEVVQL ISNEILPYAN FIPKEFVGQI MTMLNKGSIH 1560
SQSSSFTEAE IDIRLREEFS KMCFETLLQF SFSNKVTTPQ EGYISRMALS VLLKRSQDVL 1620
HRYIEDERLS GKCPLPRQQV TEIIFVLKAV STLIDSLKKT QPENVDGNTW AQVIALYPTL 1680
VECITCSSSE VCSALKEALV PFKDFMQPPA SRVQNGES 1718 
Gene Ontology
 GO:0005802; C:trans-Golgi network; IBA:RefGenome.
 GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
 GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
 GO:0006895; P:Golgi to endosome transport; ISS:HGNC.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR015403; DUF1981_SEC7_assoc.
 IPR026829; MON2. 
Pfam
 PF09324; DUF1981 
SMART
  
PROSITE
  
PRINTS