CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036840
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphatidylinositol 3-kinase regulatory subunit gamma 
Protein Synonyms/Alias
  
Gene Name
 PIK3R3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
119YNPKLDVKLMYPVSRubiquitination[1]
134YQQDQLVKEDNIDAVubiquitination[1]
144NIDAVGKKLQEYHSQubiquitination[1]
202HTQEQHSKEYIERFRubiquitination[1]
280AEDLLYGKPDGAFLIubiquitination[1]
293LIRESSKKGCYACSVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 366 AA 
Protein Sequence
MYNTVWSMDR DDADWREVMM PYSTELIFYI EMDPPAAEVN DKLRDMPDGT FLVRDASTKM 60
QGDYTLTLRK GGNNKLIKIY HRDGKYGFSD PLTFNSVVEL INHYHHESLA QYNPKLDVKL 120
MYPVSRYQQD QLVKEDNIDA VGKKLQEYHS QYQEKSKEYD RLYEEYTRTS QEIQMKRTAI 180
EAFNETIKIF EEQCHTQEQH SKEYIERFRR EGNEKEIERW LNHKGVRQKR LNVWLGIKNE 240
DADENYFINE EDENLPHYDE KTWFVEDINR VQAEDLLYGK PDGAFLIRES SKKGCYACSV 300
VADGEVKHCV IYSTARGYGF AEPYNLYSSL KELVLHYQQT SLVQHNDSLN VRLAYPVHAQ 360
MPSLCR 366 
Gene Ontology
 GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
 GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:InterPro.
 GO:0043551; P:regulation of phosphatidylinositol 3-kinase activity; IEA:GOC. 
Interpro
 IPR001720; PI3kinase_P85.
 IPR000980; SH2. 
Pfam
 PF00017; SH2 
SMART
 SM00252; SH2 
PROSITE
 PS50001; SH2 
PRINTS
 PR00678; PI3KINASEP85.
 PR00401; SH2DOMAIN.