CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019161
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Galectin-12 
Protein Synonyms/Alias
 Gal-12; Galectin-related inhibitor of proliferation 
Gene Name
 LGALS12 
Gene Synonyms/Alias
 GRIP1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
237GLVLQEPKHFTVSLRubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
 Binds lactose. May participate in the apoptosis of adipocytes. 
Sequence Annotation
 DOMAIN 49 183 Galectin 1.
 DOMAIN 212 336 Galectin 2.  
Keyword
 Alternative splicing; Apoptosis; Complete proteome; Lectin; Nucleus; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 336 AA 
Protein Sequence
MSQPSGGRAP GTRIYSWSCP TVMSPGEKLD PIPDSFILQP PVFHPVVPYV TTIFGGLHAG 60
KMVMLQGVVP LDAHRFQVDF QCGCSLCPRP DIAFHFNPRF HTTKPHVICN TLHGGRWQRE 120
ARWPHLALRR GSSFLILFLF GNEEVKVSVN GQHFLHFRYR LPLSHVDTLG IFGDILVEAV 180
GFLNINPFVE GSREYPAGHP FLLMSPRLEV PCSHALPQGL SPGQVIIVRG LVLQEPKHFT 240
VSLRDQAAHA PVTLRASFAD RTLAWISRWG QKKLISAPFL FYPQRFFEVL LLFQEGGLKL 300
ALNGQGLGAT SMNQQALEQL RELRISGSVQ LYCVHS 336 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0030395; F:lactose binding; IDA:MGI.
 GO:0097193; P:intrinsic apoptotic signaling pathway; IDA:MGI. 
Interpro
 IPR008985; ConA-like_lec_gl_sf.
 IPR013320; ConA-like_subgrp.
 IPR001079; Galectin_CRD. 
Pfam
 PF00337; Gal-bind_lectin 
SMART
 SM00908; Gal-bind_lectin
 SM00276; GLECT 
PROSITE
 PS51304; GALECTIN 
PRINTS