CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013998
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 KN motif and ankyrin repeat domain-containing protein 4 
Protein Synonyms/Alias
 Ankyrin repeat domain-containing protein 38 
Gene Name
 KANK4 
Gene Synonyms/Alias
 ANKRD38 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
642ISPSTSLKSIMKKKDubiquitination[1]
Reference
 [1] A data set of human endogenous protein ubiquitination sites.
 Shi Y, Chan DW, Jung SY, Malovannaya A, Wang Y, Qin J.
 Mol Cell Proteomics. 2011 May;10(5):M110.002089. [PMID: 20972266
Functional Description
 May be involved in the control of cytoskeleton formation by regulating actin polymerization. 
Sequence Annotation
 REPEAT 823 853 ANK 1.
 REPEAT 862 890 ANK 2.
 REPEAT 895 924 ANK 3.
 REPEAT 928 958 ANK 4.
 REPEAT 962 992 ANK 5.  
Keyword
 Alternative splicing; ANK repeat; Coiled coil; Complete proteome; Cytoplasm; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 995 AA 
Protein Sequence
MEKTDAKDQS SQGDEEKDPP KSHPYSVETP YGFHLDLDFL KYVDDIEKGN TIKRIPIHRR 60
AKQAKFSTLP RNFSLPDSGA RPPAAPPLQN WSPVVPREAS LGTQEQNQSP PLGNAPQAST 120
SRSEVSYHRK ALLAEATRQL EAAEPEDAEL TFGSGRPQLL RASSMPATLL HSRASEEPGL 180
SLGPPAPPAL PPLQGEGSVC DGTFEPAEGL AGFHSSSPRA STRIPELVQE GAEPPEGVVK 240
VPNHLPLPGP PFSFQNVLVV LEDKEDEHNA REAEVLFTPG SPTPSPPPLP SPIPENELLL 300
EEIELNISEI PPPPPVEVDM RSIGIRVTEE SLGLARVDPG SISSLKQQVS ALEGELSGRT 360
EELAQVRTAL QQQEEEIKAR EQRIRELEFT VAQLEGQFHQ ENAKDTQGQT DVMVNTDPVH 420
GLLTRESCDK GIEVNLLGSM ESESWGHRGE ENGLLWGPDG HKQGNQSPAE RVLLPQLSLP 480
QGPEQVLTSS VHSFLSTELR IEEAGTEQEG GPQGGTRGAG GFLWGSDRKT PPAGREETSS 540
NLPGKEHPGR PPSSPTDATI GQYVKKIQEL LQEQWNCLEH GYPELASAIK QPASKLSSIQ 600
SQLLSSLNLL LSAYSAQAHP PKEPPASSSS PPVEISPSTS LKSIMKKKDY GFRAGGNGTK 660
KNLQFVGVNG GYETTSSEET SGEDSTPEDL SDSEAEKKCD GPDHKHVKDA HLTCEAGQGI 720
PEGTCHAAQE SGPGEEVPHS KAERYKPSEE FLNACRALSQ HLPETGTTTD QLLRQSLNTI 780
SQEWFRVSSR KSSSPAVVAS YLHEVQPHSP HFLKLLVNLA DHNGNTALHY SVSHSNFSIV 840
KLLLETGVCN VDHQNKAGYT AVMITPLASA ETNEDMAVVW KLLREGNVNI QATQGGQTAL 900
MLGVSHDRED MVQALLSCQA DVNLQDHDGS SALMVACHHG NVDLVRLLLA HPACDSSLTD 960
KAGRTALSIA LKSPTHMEIA GLLRAHAEQG RSLGL 995 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR021939; KN_motif. 
Pfam
 PF12796; Ank_2
 PF12075; KN_motif 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS