| Tag | Content |
|---|
| CPLM ID | CPLM-011458 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 33A |
Protein Synonyms/Alias | Zinc finger and ZAK-associated protein with KRAB domain; ZZaPK; Zinc finger protein 11A; Zinc finger protein KOX31 |
Gene Name | ZNF33A |
Gene Synonyms/Alias | KIAA0065; KOX31; ZNF11; ZNF11A; ZNF33 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 3 | *****MNKVEQKSQE | ubiquitination | [1] | | 165 | KINYLGKKSDEFNAC | ubiquitination | [1] | | 189 | DETHTQEKNEVLKNR | ubiquitination | [1] | | 194 | QEKNEVLKNRNTLSH | ubiquitination | [1] | | 237 | KAVFNTQKRENAEEN | ubiquitination | [1] | | 335 | FECNECGKAFWEKSH | ubiquitination | [1] | | 340 | CGKAFWEKSHLTRHQ | ubiquitination | [1] | | 363 | FQCNECEKAFWDKSN | ubiquitination | [1] | | 368 | CEKAFWDKSNLTKHQ | ubiquitination | [1] | | 410 | QRTHTGEKPYQCNAC | ubiquitination | [1] | | 424 | CGKTFCQKSDLTKHQ | ubiquitination | [1] | | 466 | QRTHTGEKPFECLEC | ubiquitination | [1] | | 620 | CGKAFYQKSQLTQHQ | ubiquitination | [1] | | 727 | CQCNECGKIFYRKSE | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 12 83 KRAB.
ZN_FING 328 350 C2H2-type 1.
ZN_FING 356 378 C2H2-type 2.
ZN_FING 384 406 C2H2-type 3.
ZN_FING 412 434 C2H2-type 4.
ZN_FING 440 462 C2H2-type 5.
ZN_FING 468 490 C2H2-type 6.
ZN_FING 496 518 C2H2-type 7.
ZN_FING 524 546 C2H2-type 8.
ZN_FING 552 574 C2H2-type 9.
ZN_FING 580 602 C2H2-type 10.
ZN_FING 608 630 C2H2-type 11.
ZN_FING 636 658 C2H2-type 12.
ZN_FING 664 686 C2H2-type 13.
ZN_FING 692 714 C2H2-type 14.
ZN_FING 720 742 C2H2-type 15.
ZN_FING 748 770 C2H2-type 16. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 810 AA |
Protein Sequence | MNKVEQKSQE SVSFKDVTVG FTQEEWQHLD PSQRALYRDV MLENYSNLVS VGYCVHKPEV 60
IFRLQQGEEP WKQEEEFPSQ SFPVWTADHL KERSQENQSK HLWEVVFINN EMLTKEQGDV 120
IGIPFNVDVS SFPSRKMFCQ CDSCGMSFNT VSELVISKIN YLGKKSDEFN ACGKLLLNIK 180
HDETHTQEKN EVLKNRNTLS HHEETLQHEK IQTLEHNFEY SICQETLLEK AVFNTQKREN 240
AEENNCDYNE FGRTLCDSSS LLFHQISPSR DNHYEFSDCE KFLCVKSTLS KPHGVSMKHY 300
DCGESGNNFR RKLCLSHLQK GDKGEKHFEC NECGKAFWEK SHLTRHQRVH TGQKPFQCNE 360
CEKAFWDKSN LTKHQRSHTG EKPFECNECG KAFSHKSALT LHQRTHTGEK PYQCNACGKT 420
FCQKSDLTKH QRTHTGLKPY ECYECGKSFR VTSHLKVHQR THTGEKPFEC LECGKSFSEK 480
SNLTQHQRIH IGDKSYECNA CGKTFYHKSL LTRHQIIHTG WKPYECYECG KTFCLKSDLT 540
VHQRTHTGQK PFACPECGKF FSHKSTLSQH YRTHTGEKPY ECHECGKIFY NKSYLTKHNR 600
THTGEKPYEC NECGKAFYQK SQLTQHQRIH IGEKPYKCNE CGKAFCHKSA LIVHQRTHTQ 660
EKPYKCNECG KSFCVKSGLI FHERKHTGEK PYECNECGKF FRHKSSLTVH HRAHTGEKSC 720
QCNECGKIFY RKSELAQHQR SHTGEKPYEC NTCRKTFSQK SNLIVHQRRH IGENLMNEMD 780
IRNFQPQVSL HNASEYSHCG ESPDDILNVQ 810 |
Gene Ontology | GO:0005634; C:nucleus; NAS:UniProtKB. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |