CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015781
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 
Protein Synonyms/Alias
 DEAD/H box 32; DEAD/H helicase-like protein 1; DHLP1; DEAH box protein 32; HuDDX32 
Gene Name
 DHX32 
Gene Synonyms/Alias
 DDX32 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
224SSPHLISKLNSYYGNubiquitination[1]
353TSMVLFMKRIDIAGLubiquitination[1]
515AELLEIIKRIELPYAubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
 DOMAIN 72 238 Helicase ATP-binding.
 NP_BIND 85 92 ATP (By similarity).
 MOTIF 185 188 DEAH box.  
Keyword
 Alternative splicing; ATP-binding; Complete proteome; Helicase; Hydrolase; Mitochondrion; Nucleotide-binding; Nucleus; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 743 AA 
Protein Sequence
MEEEGLECPN SSSEKRYFPE SLDSSDGDEE EVLACEDLEL NPFDGLPYSS RYYKLLKERE 60
DLPIWKEKYS FMENLLQNQI VIVSGDAKCG KSAQVPQWCA EYCLSIHYQH GGVICTQVHK 120
QTVVQLALRV ADEMDVNIGH EVGYVIPFEN CCTNETILRY CTDDMLQREM MSNPFLGSYG 180
VIILDDIHER SIATDVLLGL LKDVLLARPE LKLIINSSPH LISKLNSYYG NVPVIEVKNK 240
HPVEVVYLSE AQKDSFESIL RLIFEIHHSG EKGDIVVFLA CEQVYNPRIR ANSLVMQPIS 300
QSQAEIRKQI LGSSSSGKFF CLYTEEFASK DMTPLKPAEM QEANLTSMVL FMKRIDIAGL 360
GHCDFMNRPA PESLMQALED LDYLAALDND GNLSEFGIIM SEFPLDPQLS KSILASCEFD 420
CVDEVLTIAA MVTAPNCFSH VPHGAEEAAL TCWKTFLHPE GDHFTLISIY KAYQDTTLNS 480
SSEYCVEKWC RDYFLNCSAL RMADVIRAEL LEIIKRIELP YAEPAFGSKE NTLNIKKALL 540
SGYFMQIARD VDGSGNYLML THKQVAQLHP LSGYSITKKM PEWVLFHKFS ISENNYIRIT 600
SEISPELFMQ LVPQYYFSNL PPSESKDILQ QVVDHLSPVS TMNKEQQMCE TCPETEQRCT 660
LQ 662 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004386; F:helicase activity; IEA:UniProtKB-KW. 
Interpro
 IPR011709; DUF1605.
 IPR007502; Helicase-assoc_dom.
 IPR014001; Helicase_ATP-bd.
 IPR027417; P-loop_NTPase. 
Pfam
 PF04408; HA2
 PF07717; OB_NTP_bind 
SMART
 SM00847; HA2 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER 
PRINTS