CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021888
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hepatoma-derived growth factor-related protein 3 
Protein Synonyms/Alias
 HRP-3 
Gene Name
 Hdgfrp3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
10RPRPREYKAGDLVFAubiquitination[1]
66PKDLFPYKEYKDKFGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Enhances DNA synthesis and may play a role in cell proliferation (By similarity). 
Sequence Annotation
 DOMAIN 11 68 PWWP.
 MOTIF 135 147 Nuclear localization signal (Potential).
 MOD_RES 177 177 Phosphoserine.
 MOD_RES 178 178 Phosphoserine.
 MOD_RES 179 179 Phosphoserine.  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Growth factor; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 202 AA 
Protein Sequence
MARPRPREYK AGDLVFAKMK GYPHWPARID ELPEGAVKPP ANKYPIFFFG THETAFLGPK 60
DLFPYKEYKD KFGKSNKRKG FNEGLWEIEN NPGVKFTGYQ TIQQQSSSET EGEGGNTADA 120
SSEEEGDRVE DGKGKRKNEK GGSKRKKSYT SKKSSKQSRK SPGDEDDKDC KEEENKSSSE 180
GGDAGNDTRN TTADLQKAGE GT 202 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003682; F:chromatin binding; NAS:UniProtKB.
 GO:0008283; P:cell proliferation; ISS:MGI. 
Interpro
 IPR000313; PWWP. 
Pfam
 PF00855; PWWP 
SMART
 SM00293; PWWP 
PROSITE
 PS50812; PWWP 
PRINTS