CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015238
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 AT-hook DNA-binding motif-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Ahdc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
79RRPPVLAKGDDLLPPacetylation[1, 2]
942RAAETFPKLAPPPSAacetylation[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
 DNA_BIND 395 407 A.T hook 1.
 DNA_BIND 541 553 A.T hook 2.
 MOD_RES 593 593 Phosphoserine (By similarity).
 MOD_RES 825 825 Phosphoserine.
 MOD_RES 842 842 Phosphoserine (By similarity).
 MOD_RES 1392 1392 Phosphoserine (By similarity).  
Keyword
 Complete proteome; DNA-binding; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1594 AA 
Protein Sequence
MRVKPQGLVV TSSAVCSSPD YLREPKYYPG GPPTPRPLLP TRPPASPPDK AFSTHTFSEN 60
PRPPPRRDPS SRRPPVLAKG DDLLPPRAAR PVSQAHCPSP APDNSSLRHW DNGRVNLRPV 120
VQLIDIMKDL TRLSQDLQHS GVHLDCGGLR LSRPPAPPPG DLQYSFFSSP SLANSIRSPE 180
ERANPHTKSE RPSHPLYEPE PEPRDSPQPG QGHGPGAAAT ATGLPPEPEP DGPDYSELAD 240
ADILSELASL TCPEAQLLEA QALEPPSPQP EPQLLDPQPR FLDPQALEPL GEGLELPPLQ 300
PLADPLGLPS LTLQALDTLP DSLESQLLDP QALDPLPKLL DVPGRRLEPQ QSLGHCQLAE 360
PLRLDLCSPH GPPGPEGHPK YALRRTDRPK ILCRRRKAGR GRKADSGPEG RLLPLPMPTG 420
LAAALAEPPP LPPPPPPTLS GPGPVPELEP ESSQTPMVPT RKGKCRGVRR MVVKMAKIPV 480
SLGRRNKTTY KVSSLSSSLS VEGKELGLRV SSEPTPLLKM KNNGRNVVVV FPPGEMPIIL 540
KRKRGRPPKN LLLGPGKPKE PTVVAAEAAT VTAATMAMPE VKKRRRRKQK LASPQPSYAA 600
DANDSKAEYS DVLAKLAFLN RQSQCAGRCS PPRCWTPSEP ESVHQAPDTQ SISQFLHRVQ 660
GFRRRGGKTG GFGGRGGGHA AKAARCSFSD FFEGIGKKKK VVAVAAPGLV GPGLTELGHP 720
RKRGRGEVDA VTGKPKRKRR SRKNGTLFPE QVPSGPGFGE AGAEWVGDKG GGWAPHHGHP 780
GGQAGRNCGF QGTEARAFAS TGLESGASGR GSYYAGAPSG QTELSQERQN LFTGYFRSLL 840
DSDDSSDLLD FALSASRPES RKASGTYAGP PSSALPAQRG LATFPSRGAK ASPVAVGSSG 900
AGADPSFQPV LPSRQTFPPG RATSYGITPA TSDCRAAETF PKLAPPPSAV ARSPTTHPPA 960
NTYPPQYGGY GAGQSVFASA KPFSGQDCAN SKDCSFAYGS GNSLPASPSS AHSAGYAPPP 1020
TGGPCLPPSK ASFFNSSEGG PFSGSAPTPL RCDSRASTVS PGGYMVPKGT TASAASVASS 1080
SSSSFQPSPE NCRQFVGASQ WPFRQGYGGL DWASEAFSQL YNPNFDCHGS EPNVILDISN 1140
YTPQKVKQQT AVSETFSESS SDSTQFSQPV GGGGFRRANS EASSSEGQSS LSSLEKLMMD 1200
WNEASSAPGY NWNQSVLFQS SSKPGRGRRK KVDLFEASHL GFSTSTSATA SGYPSKRSTG 1260
PRQPRGGRGS GACSAKKERG GTAAKAKFIP KPQPVNPLFQ DSPDLGLDYY SGDSSMSPLP 1320
SQSRAFGVGE RDPCDFMGPY SMNPSTPSDG TFGQGFHCDS PSLGAAELDG KHFPPLAHPP 1380
TVFDAGLQKA YSPTCSPTLG FKEELRPPPS KLTACEPLKH GLQGASLSHA AQAHLSCRDL 1440
PLGQPHYDSP SCKGTAYWYP PGSAARSPPY EGKVGSGLLA DFLGRTEAVC LSAPHLASPP 1500
ATPKADKEPL EMARPPGPPR GPAAATAGYG CPLLSDLTLS PVPRDSLLPL QDTAYRYPGF 1560
MPQAHPGLGG GPKSGFLGPM AEPHPEDTFT VTSL 1594 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW. 
Interpro
 IPR017956; AT_hook_DNA-bd_motif. 
Pfam
  
SMART
 SM00384; AT_hook 
PROSITE
  
PRINTS