CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032763
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sodium/hydrogen exchanger 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_106600 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
658LASQGSDKERLALSSacetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842] 
Functional Description
  
Sequence Annotation
  
Keyword
 Antiport; Complete proteome; Ion transport; Membrane; Reference proteome; Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1361 AA 
Protein Sequence
MGEKGALGEV EARGVAFPSF ADELTREKRR KCLDNSGKDI FAALPDEPQQ AASEECLSFT 60
KRKTGKEDPV PRGPLCGSSL GCTYSGREPS SSGRCHLSPQ ESSQDGEKLK EAANIPWRRL 120
SGFKLGDGGG ARFSPSVCPS AACSSSASLL SRSTVLRGSS LSPHSLPSSF LAVSLSSFFP 180
PKRSSSPLTP SSSSDSSLSS TSLILSGPSS LPLCFPSSSR LPSCFSVSPF SVSVALLACV 240
SPAPHAPAVS HCRYTKRQTG GKAAGEEHGA RLTRVSFLRY FRFPWRFLSW VRKAAERKGR 300
VEGRATAVSK TRQIKRGFCR SLCVSGTLWL FVLFHLLSVV CEGVPRSETD HRGLPLETKK 360
LAADSAPSLP RAHLPLPSPL AESSRHRRLA SESSSSSSPS PSSSSSPSSS SSPSPSSPSS 420
SSSPSSSPSS PSSSSSPSPS SPSSSRSSSP SLGSRAMSFL LGRGSENAQK TEDQKGDSVS 480
PSSPSPSPTA AALDAPLLAG VSSGASETVS SSGAKGEASG AQNDPAKTET AATRPEPESA 540
STSASPPTRS PAASTEGTPS SALDHPDGEK DEAGGAEREE GEKGSKSREE PPPPVFRVSS 600
TSPSNAAVFV PAVFQQNSGE GNHVTLTIPL EVLPSLAAAG ETAAPHPEEK LASQGSDKER 660
LALSSLQWLP ARESGAREGE ASLHHMGEKR RRGALAQMGA SGEEVPETSP ASLEELSSNE 720
REMVLSAGLL TLLLVLSVSL VLSHVSRKCH LRWLQMPVAA TLLGLLVGAV LKFGLKVQGP 780
ILGSVLAMNE DVFFVMLLPP IIFEGGLSLS EGSLSGPFMR NFGAIMWLAC FCTILSFCWV 840
GTLMFFGGVL GLSMFLTVRQ AFAFGALISS TDPVSVLALF KELHAKKLIH VLVFGESLLN 900
DAISIVLYRT IASEDTASVG SAILAFFLTF FVSLVIGLAV GLFCALTYKY MDLHKEENQT 960
LESALLLLFP WMAYLVADGL GYSGIVAICF CGVTIGKYAV PNLSTSARTA SRSVFNSFSL 1020
LAETVVFAFL GLAVFSFDQP LHDELAVGLY VLGFVATFSA RAVSVFVTCT LINLFRTNAK 1080
ITPQQQLALV LCGLRGAIAF ALSERARRDF GGKEGAALLS LTLFLALFTI LVLGVHTPEG 1140
LRRQQGEGGA REVAMTALPL KGRQAPGLRA EASGETEERR PSGKVSARCE AKGGDTDDED 1200
APRFRAPGLE RDEMRGRERR EDERSREGSC GRGERETGVE DPFTEEDFDD VRVALPDALR 1260
ASALLSDSEN QEFHSEEESW TERIESFSAT PESLPVVVGR GGMRGDRRRD SISEEMRDRV 1320
PEKAGAQGFE LQNGWQPNGH QNGVERETDA RETIVGKRQV L 1361 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
 GO:0006885; P:regulation of pH; IEA:InterPro. 
Interpro
 IPR006153; Cation/H_exchanger.
 IPR018422; Cation/H_exchanger_CPA1.
 IPR004709; NaH_exchanger. 
Pfam
 PF00999; Na_H_Exchanger 
SMART
  
PROSITE
  
PRINTS
 PR01084; NAHEXCHNGR.