CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034048
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 DNA topoisomerase 3-beta-1 
Protein Synonyms/Alias
  
Gene Name
 Top3b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
75GKYNKWDKVDPAELFacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 289 AA 
Protein Sequence
MKTVLMVAEK PSLAQSIAKI LSRGNMSSHK GLNGACSVHK YTGTFAGQPV HFKMTSVCGH 60
VMTLDFLGKY NKWDKVDPAE LFSQAPTEKK EANPKLNMVK FLQVEGRGCD YVVLWLDCDK 120
EGENICFEVL DAVLPVMNNA HNGEKTVFRA RFSSITDTDI CNAMTRLSEP DHNEALSVDA 180
RQELDLRIGC AFTRFQTKYF QGKYGDLDSS LISFGPCQTP TLGFCVERHD KIQSFKPETY 240
WVLQAKVHTD KEESLLLDWD RVRVFDWEIA QMFLNMTKLE KEAWVEATS 289 
Gene Ontology
 GO:0000793; C:condensed chromosome; IDA:MGI.
 GO:0003917; F:DNA topoisomerase type I activity; IEA:InterPro.
 GO:0007059; P:chromosome segregation; IMP:MGI.
 GO:0006265; P:DNA topological change; IEA:InterPro. 
Interpro
 IPR000380; Topo_IA.
 IPR003601; Topo_IA_2.
 IPR013497; Topo_IA_cen.
 IPR013824; Topo_IA_cen_sub1.
 IPR023405; Topo_IA_core_domain.
 IPR006171; Toprim_domain. 
Pfam
 PF01131; Topoisom_bac
 PF01751; Toprim 
SMART
 SM00436; TOP1Bc
 SM00493; TOPRIM 
PROSITE
  
PRINTS