| Tag | Content |
|---|
| CPLM ID | CPLM-019013 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein TBRG4 |
Protein Synonyms/Alias | Cell cycle progression restoration protein 2; Cell cycle progression protein 2; FAST kinase domain-containing protein 4; Transforming growth factor beta regulator 4 |
Gene Name | TBRG4 |
Gene Synonyms/Alias | CPR2; FASTKD4; KIAA0948 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 163 | LGIPKASKELQSVEQ | ubiquitination | [1] | | 391 | KELQETLKGLLGSAD | ubiquitination | [1] | | 449 | QSPPPGSKRLAFLRW | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | May play a role in cell cycle progression. |
Sequence Annotation | DOMAIN 561 619 RAP. |
Keyword | Alternative splicing; Complete proteome; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 631 AA |
Protein Sequence | MAAHLVKRCT CLLREAARQA PAMAPVGRLR LAWVAHKTLT SSATSPISHL PGSLMEPVEK 60
ERASTPYIEK QVDHLIKKAT RPEELLELLG GSHDLDSNQA AMVLIRLSHL LSEKPEDKGL 120
LIQDAHFHQL LCLLNSQIAS VWHGTLSKLL GSLYALGIPK ASKELQSVEQ EVRWRMRKLK 180
YKHLAFLAES CATLSQEQHS QELLAELLTH LERRWTEIED SHTLVTVMMK VGHLSEPLMN 240
RLEDKHVLNR AQDITLPHLC SVLLAFARLN FHPDQEDQFF SLVHEKLGSE LPGLEPALQV 300
DLVWALCVLQ QAREAELQAV LHPEFHIQFL GGKSQKDQNT FQKLLHINAT ALLEYPEYSG 360
PLLPASAVAP GPSALDRKVT PLQKELQETL KGLLGSADKG SLEVATQYGW VLDAEVLLDS 420
DGEFLPVRDF VAPHLAQPTG SQSPPPGSKR LAFLRWEFPN FNSRSKDLLG RFVLARRHIV 480
AAGFLIVDVP FYEWLELKSE WQKGAYLKDK MRKAVAEELA K 521 |
Gene Ontology | GO:0005739; C:mitochondrion; IDA:UniProtKB. GO:0004672; F:protein kinase activity; IEA:InterPro. GO:0007050; P:cell cycle arrest; TAS:UniProtKB. GO:0045333; P:cellular respiration; ISS:UniProtKB. GO:0000080; P:G1 phase of mitotic cell cycle; TAS:UniProtKB. GO:0008284; P:positive regulation of cell proliferation; TAS:UniProtKB. GO:0006468; P:protein phosphorylation; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |