CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025840
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tripartite motif-containing 25 variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
287EEKRVNSKFDTIYQIubiquitination[1]
334KLRGISTKPVYIPEVubiquitination[1]
363IDLKNELKQCIGRLQubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 644 AA 
Protein Sequence
ERGCSSCVPT PGSAMAELCP LAEELSCSIC LEPFKEPVTT PCGHNFCGSC LNETWAVQGS 60
PYLCPQCRAV YQARPQLHKN TVLCNVVEQF LQADLAREPP ADGWTPPARA SAPSPNAQVA 120
CDHCLKEAAV KTCLVCMASF CQEHLQPHFD SPAFQDHPLQ PPVRDLLRRK CSQHNRLREF 180
FCPEHSECIC HICLVEHKAC SPASLSQASA DLEATLRHKL TVMYSQINGA SRALDDVRNR 240
QQDVRMTANR KVEQLQQEYT EMKALLDASE TTSTRKIKEE EKRVNSKFDT IYQILLKKKS 300
EIQTLKEEIE QSLTKRDEFE FLEKASKLRG ISTKPVYIPE VELNHKLIKG IHQSTIDLKN 360
ELKQCIGRLQ ELTPSSGDPG EHDPASTHKS TRPVKKVSKE EKKSKKPPPV PALPSKLPTF 420
GAPEQLVDLK QAGLEAAAKA TSSHPNSTSL KAKVLETFLA KSRPELLEYY IKVILDYNTA 480
HNKVALSECY TVASVAEMPQ NYRPHPQRFT YCSQVLGLHC YKKGIHYWEV ELQKNNFCGV 540
GICYGSMNRQ GPESRLGRNS ASWCVEWFNT KISAWHNNVE KTLPSTKATR VGVLLNCDHG 600
FVIFFAVADK VHLMYKFRVD FTEALYPAFW VFSAGATLSI CSPK 644 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001870; B30.2/SPRY.
 IPR003879; Butyrophylin.
 IPR008985; ConA-like_lec_gl_sf.
 IPR006574; PRY.
 IPR018355; SPla/RYanodine_receptor_subgr.
 IPR003877; SPRY_rcpt.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF00622; SPRY 
SMART
 SM00589; PRY
 SM00184; RING
 SM00449; SPRY 
PROSITE
 PS50188; B302_SPRY
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS
 PR01407; BUTYPHLNCDUF.