UniProt Accession

 IF1_ECOLI; P69222; P02998 

Genbank Protein ID

 Y00373; M63145; L10383; U00096; AP009048 

Genbank Nucleotide ID

 CAA68446.1; AAC36912.1; AAA03232.1; AAC73970.1; BAA35602.1 

Protein Name

 Translation initiation factor IF-1 

Protein Synonyms/Alias

  

Gene Name

 infA 

Gene Synonyms/Alias

 b0884; JW0867 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
39	VTAHISGKMRKNYIR	acetylation	[1]
52	IRILTGDKVTVELTP	acetylation	[1]
64	LTPYDLSKGRIVFRS	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3. 

Sequence Annotation

 DOMAIN 2 72 S1-like.  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Initiation factor; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 72 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0043022; F:ribosome binding; IDA:EcoCyc.
 GO:0003743; F:translation initiation factor activity; IEA:HAMAP. 

Interpro

 IPR012340; NA-bd_OB-fold.
 IPR022967; RNA-binding_domain_S1.
 IPR006196; RNA-binding_domain_S1_IF1.
 IPR004368; TIF_IF1. 

Pfam

 PF01176; eIF-1a 

SMART

 SM00316; S1 

PROSITE

 PS50832; S1_IF1_TYPE 

PRINTS