CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030760
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Acyl-CoA synthetase family member 2, mitochondrial 
Protein Synonyms/Alias
 cDNA FLJ51819, weakly similar to Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) 
Gene Name
 ACSF2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
609ISHFKIPKYIVFVTNubiquitination[1]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 640 AA 
Protein Sequence
MAVYVGMLRL GRLCAGSSGV LGARAALSRS WQEARLQGVR FLSARGGMEA GRQRISVPSS 60
FTASAAAHSR EVDRMVSTPI GGLSYVQGCT KKHLNSKTVG QCLETTAQRV PEREALVVLH 120
EDVRLTFAQL KEEVDKAASG LLSIGLCKGD RLGMWGPNSY AWVLMQLATA QAGIILVSVN 180
PAYQAMELEY VLKKVGCKAL VFPKQFKTQQ YYNVLKQICP EVENAQPGAL KSQRLPDLTT 240
VISVDAPLPG TLLLDEVVAA GSTRQHLDQL QYNQQFLSCH DPINIQFTSG TTGSPKGATL 300
SHYNIVNNSN ILGERLKLHE KTPEQLRMIL PNPLYHCLGS VAGTMMCLMY GATLILASPI 360
FNGKKALEAI SRERGTFLYG TPTMFVDILN QPDFSSYDIS TMCGGVIAGS PAPPELIRAI 420
INKINMKDLV VAYGTTENSP VTFAHFPEDT VEQKAESVGR IMPHTEARIM NMEAGTLAKL 480
NTPGELCIRG YCVMLGYWGE PQKTEEAVDQ DKWYWTGDVA TMNEQGFCKI VGRSKDMIIR 540
GGENIYPAEL EDFFHTHPKV QEVQVVGVKD DRMGEEICAC IRLKDGEETT VEEIKAFCKG 600
KISHFKIPKY IVFVTNYPLT ISGKIQKFKL REQMERHLNL 640 
Gene Ontology
 GO:0016874; F:ligase activity; IEA:UniProtKB-KW. 
Interpro
 IPR020845; AMP-binding_CS.
 IPR000873; AMP-dep_Synth/Lig.
 IPR025110; DUF4009. 
Pfam
 PF00501; AMP-binding
 PF13193; DUF4009 
SMART
  
PROSITE
 PS00455; AMP_BINDING 
PRINTS