CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034442
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger CCCH-type antiviral protein 1 
Protein Synonyms/Alias
  
Gene Name
 Zc3hav1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
295ADVTQKFKYLGTQDRubiquitination[1]
311QLSSVSSKAAGVRGPubiquitination[1]
497SPTGFGIKSAVTGGKubiquitination[1]
504KSAVTGGKEAVYSGVubiquitination[1]
687STPSFVEKTLNSVFTubiquitination[1]
779RPVFVSSKDVEQKRRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 996 AA 
Protein Sequence
MTDPEVFCFI TKILCAHGGR MTLEELLGEI SLPEAQLYEL LKAAGPDRFV LLETGDQAGI 60
TRSVVATTRA RVCRRKYCQR PCDSLHLCKL NLLGRCHYAQ SQRNLCKYSH DVLSEQNFQV 120
LKNHELSGLN QEELAVLLVQ SDPFFMPEIC KSYKGEGRKQ ICGQPQPCER LHICEHFTRG 180
NCSYLNCLRS HNLMDRKVLA IMREHGLSSD VVQNIQDICN NKHTRRNPPS MRAPHPHRRG 240
GAHRDRSKSR DRFHHNSLEV LSTVSPLGSG PPSPDVTGCK DPLEDVSADV TQKFKYLGTQ 300
DRAQLSSVSS KAAGVRGPSQ MRASQEFLED GDPDGLFSRN RSDSSTSRTS AAGFPLVAAQ 360
RNEAGAMKMG MPSGHHVEVK GKNEDIDRVP FLNSYIDGVT MEEATVSGIL GKRATDNGLE 420
EMILSSNHQK SVAKTQDPQT AGRITDSGQD TAFLHSKYEE NPAWPGTSTH NGPNGFSQIM 480
DETPNVSKSS PTGFGIKSAV TGGKEAVYSG VQSLRSHVLA MPGETTTPVQ GSNRLPPSPL 540
SSSTSHRVAA SGSPGKSSTH ASVSPASEPS RMMMMMSDPA EYSLCYIVNP VSPRMDDHGL 600
KEICLDHLYR GCQQVNCNKN HFHLPYRWQL FILPTWMDFQ DMEYIERAYC DPQIEIIVIE 660
KHRINFKKMT CDSYPIRRLS TPSFVEKTLN SVFTTKWLWY WRNELNEYTQ YGHESPSHTS 720
SEINSAYLES FFHSCPRGVL QFHAGSQNYE LSFQGMIQTN IASKTQRHVV RRPVFVSSKD 780
VEQKRRGPDH QPVMPQADAL TLFSSPQRNA STVSSNEYEF IELNNQDEEY AKISEQFKAS 840
MKQFKIVTIK RIWNQKLWDT FERKKQKMKN KTEMFLFHAV GRIHMDYICK NNFEWILHGN 900
REIRYGKGNY FTKEAMYSHK SCSYDSRGTV MFVARVLVGS VIEGNMTLSS PPALYDSCVD 960
TRLNPSVFVI FRKEQIYPEY VIEYMELEKE KGCIIS 996 
Gene Ontology
 GO:0005737; C:cytoplasm; ISO:MGI.
 GO:0017151; F:DEAD/H-box RNA helicase binding; ISO:MGI.
 GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0071360; P:cellular response to exogenous dsRNA; IDA:MGI.
 GO:0032781; P:positive regulation of ATPase activity; ISO:MGI.
 GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISO:MGI.
 GO:0032481; P:positive regulation of type I interferon production; IDA:MGI. 
Interpro
 IPR012317; Poly(ADP-ribose)pol_cat_dom.
 IPR004170; WWE-dom.
 IPR000571; Znf_CCCH. 
Pfam
 PF00644; PARP 
SMART
  
PROSITE
 PS51059; PARP_CATALYTIC
 PS50918; WWE
 PS50103; ZF_C3H1 
PRINTS