CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017242
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BRO1 domain-containing protein BROX 
Protein Synonyms/Alias
 BRO1 domain- and CAAX motif-containing protein 
Gene Name
 Brox 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
148KEVHRSLKIAAGIFKubiquitination[1]
334NGFIYFQKIPTEAPQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 DOMAIN 90 408 BRO1.
 MOD_RES 408 408 Cysteine methyl ester (By similarity).
 LIPID 408 408 S-farnesyl cysteine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Lipoprotein; Membrane; Methylation; Prenylation; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 411 AA 
Protein Sequence
MTHWFHRNPL KATAPVSFNY YGMITGPPAS KICNDLRSAR TRLLELFTDL SCNPETMKNA 60
ADLYFSLLQG FINSVGDSTQ ESKLRYIQNF KWTDTLQGHV PSAQQDAVFE LISMGFNVAL 120
WYTKYASRLA GKENITEDEA KEVHRSLKIA AGIFKHLKES HIPKLLTPAE KGRDLEARLI 180
DAYIIQCQAE AQEVTIARAI ELKHAPGLIA ALAYDTASFY QKADHTLSSL EPAHSAKWRK 240
YLHLKMCFYT AYAYCYHGQT LLASDKCGEA IRSLQEAEKL YAEAEALCKE YGETKGPGPT 300
AKPSGHLFFR KLGSLVKNTL DKCQRENGFI YFQKIPTEAP QLELKANYGL VEPVPFEFPP 360
MSAHWTPEAL AAFDLTKRPK DDSVKPKPEE DVKPVKEPDI RPQKDTGCSV S 411 
Gene Ontology
 GO:0016020; C:membrane; IEA:UniProtKB-SubCell. 
Interpro
 IPR004328; BRO1_dom. 
Pfam
 PF03097; BRO1 
SMART
 SM01041; BRO1 
PROSITE
 PS51180; BRO1 
PRINTS