CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004712
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Guanine nucleotide-binding protein subunit gamma 
Protein Synonyms/Alias
  
Gene Name
 STE18 
Gene Synonyms/Alias
 YJR086W; J1866 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
26QQQQLSLKIKQLKLKubiquitination[1]
41RINELNNKLRKELSRubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Implicated in the pheromone A- and alpha-factor response pathway. The beta and gamma chains of the putative yeast mating response pathway G protein play a positive role in initiation of the mating response. 
Sequence Annotation
 MOD_RES 107 107 Cysteine methyl ester.
 LIPID 106 106 S-palmitoyl cysteine.
 LIPID 107 107 S-farnesyl cysteine.  
Keyword
 3D-structure; Complete proteome; Lipoprotein; Membrane; Methylation; Palmitate; Pheromone response; Prenylation; Reference proteome; Transducer. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 110 AA 
Protein Sequence
MTSVQNSPRL QQPQEQQQQQ QQLSLKIKQL KLKRINELNN KLRKELSRER ITASNACLTI 60
INYTSNTKDY TLPELWGYPV AGSNHFIEGL KNAQKNSQMS NSNSVCCTLM 110 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005834; C:heterotrimeric G-protein complex; IDA:SGD.
 GO:0004871; F:signal transducer activity; IMP:SGD.
 GO:0031684; P:heterotrimeric G-protein complex cycle; IMP:SGD.
 GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD. 
Interpro
 IPR015898; G-protein_gamma-like_dom. 
Pfam
 PF00631; G-gamma 
SMART
 SM00224; GGL 
PROSITE
 PS50058; G_PROTEIN_GAMMA 
PRINTS