| Tag | Content |
|---|
| CPLM ID | CPLM-004559 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Catalase |
Protein Synonyms/Alias | |
Gene Name | Cat |
Gene Synonyms/Alias | CG6871 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 219 | GYGSHTFKLINAKGE | acetylation | [1] | | 241 | FKTDQGIKNLDVKTA | acetylation | [1] | | 246 | GIKNLDVKTADQLAS | acetylation | [1] | | 291 | YEQAKKFKYNPFDVT | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. |
Sequence Annotation | MOTIF 504 506 Microbody targeting signal (Potential).
ACT_SITE 73 73 By similarity.
ACT_SITE 146 146 By similarity.
METAL 356 356 Iron (heme axial ligand) (By similarity). |
Keyword | Complete proteome; Direct protein sequencing; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase; Peroxisome; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 506 AA |
Protein Sequence | MAGRDAASNQ LIDYKNSQTV SPGAITTGNG APIGIKDASQ TVGPRGPILL QDVNFLDEMS 60
HFDRERIPER VVHAKGAGAF GYFEVTHDIT QYCAAKIFDK VKKRTPLAVR FSTVGGESGS 120
ADTARDPRGF AVKFYTEDGV WDLVGNNTPV FFIRDPILFP SFIHTQKRNP QTHLKDPDMF 180
WDFLTLRPES AHQVCILFSD RGTPDGYCHM NGYGSHTFKL INAKGEPIYA KFHFKTDQGI 240
KNLDVKTADQ LASTDPDYSI RDLYNRIKTC KFPSWTMYIQ VMTYEQAKKF KYNPFDVTKV 300
WSQKEYPLIP VGKMVLDRNP KNYFAEVEQI AFSPAHLVPG VEPSPDKMLH GRLFSYSDTH 360
RHRLGPNYLQ IPVNCPYKVK IENFQRDGAM NVTDNQDGAP NYFPNSFNGP QECPRARALS 420
SCCPVTGDVY RYSSGDTEDN FGQVTDFWVH VLDKCAKKRL VQNIAGHLSN ASQFLQERAV 480
KNFTQVHADF GRMLTEELNL AKSSKF 506 |
Gene Ontology | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. GO:0004096; F:catalase activity; IDA:FlyBase. GO:0020037; F:heme binding; IEA:InterPro. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0008340; P:determination of adult lifespan; TAS:FlyBase. GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW. GO:0035206; P:regulation of hemocyte proliferation; IMP:FlyBase. GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |