CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026489
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LanC lantibiotic synthetase component C-like 2 (Bacterial) 
Protein Synonyms/Alias
 Protein Lancl2 
Gene Name
 Lancl2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
75KIVPNLIKRIQTKIKubiquitination[1]
82KRIQTKIKDLLQQMEacetylation[2]
134LRSLDYVKRTLRNLSacetylation[2]
290ETLTEMVKPSIDYVRubiquitination[1]
339LRAYQVFKEEKYLKEacetylation[2]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 450 AA 
Protein Sequence
MGETMSKRLK FHLGEAEMEE RSFPNPFLDY EVAASATGFA SGTAEETGRV CPLPTTEDPG 60
LPFHPNGKIV PNLIKRIQTK IKDLLQQMEE GLKTADPHDC SAYTGWTGIA LLYLQLYRVT 120
GDQTYLLRSL DYVKRTLRNL SGRRVTFLCG DAGPLAVGAV IYHKLKSECE SQECITKLLQ 180
MHRTIVCQES ELPDELLFGR AGYLYALLYL NTEIGPGTVG ETAIKEVVTA IIESGKRLSR 240
EERKSERCPL LYQWHRKQYV GAAHGMAGIY YMLMQPEAKV DQETLTEMVK PSIDYVRHKK 300
FRSGNYPSSL SNETDRLVHW CHGAPGVIHM LLRAYQVFKE EKYLKEAMEC SDVIWQRGLL 360
RKGYGICHGT AGNGYSFLSL YQLTQDKKYL YRACKFAEWC LDYGAHGCRI PDRPYSLFEG 420
MAGAVHFLSD MLVPETARFP AFELGFVQKD 450 
Gene Ontology
 GO:0030864; C:cortical actin cytoskeleton; IEA:Compara.
 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0005886; C:plasma membrane; ISS:UniProtKB.
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:Compara.
 GO:0070273; F:phosphatidylinositol-4-phosphate binding; IEA:Compara.
 GO:0010314; F:phosphatidylinositol-5-phosphate binding; IEA:Compara.
 GO:0008152; P:metabolic process; IEA:GOC.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
 GO:0009789; P:positive regulation of abscisic acid mediated signaling pathway; IEA:Compara. 
Interpro
 IPR008928; 6-hairpin_glycosidase-like.
 IPR012341; 6hp_glycosidase.
 IPR007822; LANC-like.
 IPR020464; LanC-like_prot_euk. 
Pfam
 PF05147; LANC_like 
SMART
  
PROSITE
  
PRINTS
 PR01951; LANCEUKARYTE.
 PR01950; LANCSUPER.