CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026512
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA0899 protein 
Protein Synonyms/Alias
  
Gene Name
 Ap2a2 
Gene Synonyms/Alias
 mKIAA0899 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
35AKMPAVSKGDGMRGLubiquitination[1]
64AEIKRINKELANIRSubiquitination[1]
194GDTMDSVKQSAALCLubiquitination[1]
598LRSDSQLKNADVELQubiquitination[1]
643RESSILAKLKKKKGPubiquitination[1]
648LAKLKKKKGPSTVTDubiquitination[1]
660VTDLEETKRERSIDVubiquitination[1]
870QDFFQRWKQLSNPQQubiquitination[1]
884QEVQNIFKAKHPMDTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Membrane. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 967 AA 
Protein Sequence
AAPRSRALRR DRRARAVLAR RRGRSRGAKM PAVSKGDGMR GLAVFISDIR NCKSKEAEIK 60
RINKELANIR SKFKGDKALD GYSKKKYVCK LLFIFLLGHD IDFGHMEAVN LLSSNRYTEK 120
QIGYLFISVL VNSNSELIRL INNAIKNDLA SRNPTFMGLA LHCIANVGSR EMAEAFAGEI 180
PKILVAGDTM DSVKQSAALC LLRLYRTSPD LVPMGDWTSR VVHLLNDQHL GVVTAATSLI 240
TTLAQKNPEE FKTSVSLAVS RLSRIVTSAS TDLQDYTYYF VPAPWLSVKL LRLLQCYPPP 300
DPAVRGRLTE CLETILNKAQ EPPKSKKVQH SNAKNAVLFE AISLIIHHDS EPNLLVRACN 360
QLGQFLQHRE TNLRYLALES MCTLASSEFS HEAVKTHIET VINALKTERD VSVRQRAVDL 420
LYAMCDRSNA QQIVAEMLSY LETADYSIRE EIVLKVAILA EKYAVDYTWY VDTILNLIRI 480
AGDYVSEEVW YRVIQIVINR DDVQGYAAKT VFEALQAPAC HENLVKVGGY ILGEFGNLIA 540
GDPRSSPLIQ FNLLHSKFHL CSVPTRALLL STYIKFVNLF PEVKATIQDV LRSDSQLKNA 600
DVELQQRAVE YLRLSTVAST DILATVLEEM PPFPERESSI LAKLKKKKGP STVTDLEETK 660
RERSIDVNGG PEPVPASTSA ASTPSPSADL LGLGAVPPAP TGPPPSSGGG LLVDVFSDSA 720
SAVAPLAPGS EDNFARFVCK NNGVLFENQL LQIGLKSEFR QNLGRMFIFY GNKTSTQFLN 780
FTPTLICADD LQTNLNLQTK PVDPTVDGGA QVQQVVNIEC ISDFTEAPVL NIQFRYGGTF 840
QNVSVKLPIT LNKFFQPTEM ASQDFFQRWK QLSNPQQEVQ NIFKAKHPMD TEITKAKIIG 900
FGSALLEEVD PNPANFVGAG IIHTKTTQIG CLLRLEPNLQ AQMYRLTLRT SKDTVSQRLC 960
ELLSEQF 967 
Gene Ontology
 GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
 GO:0030117; C:membrane coat; IDA:MGI.
 GO:0030141; C:secretory granule; TAS:MGI.
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; TAS:MGI.
 GO:0016192; P:vesicle-mediated transport; TAS:MGI. 
Interpro
 IPR017104; AP2_complex_asu.
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR002553; Clathrin/coatomer_adapt-like_N.
 IPR013038; Clathrin_a-adaptin_app_Ig-like.
 IPR003164; Clathrin_a-adaptin_app_sub_C.
 IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
 IPR015873; Clathrin_a/coatomer_app_sub_C.
 IPR009028; Coatomer/calthrin_app_sub_C.
 IPR013041; Coatomer/clathrin_app_Ig-like. 
Pfam
 PF01602; Adaptin_N
 PF02296; Alpha_adaptin_C
 PF02883; Alpha_adaptinC2 
SMART
 SM00809; Alpha_adaptinC2 
PROSITE
  
PRINTS