UniProt Accession

 Q5SQT9_HUMAN; Q5SQT9 

Genbank Protein ID

 AF318066; CH471083 

Genbank Nucleotide ID

 AAL27183.1; EAW54378.1 

Protein Name

 SAR1 gene homolog A (S. cerevisiae), isoform CRA_a 

Protein Synonyms/Alias

 Small GTP-binding protein 

Gene Name

 SAR1A 

Gene Synonyms/Alias

 hCG_1787550 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
27	GLYKKSGKLVFLGLD	ubiquitination	[1, 2]
46	TTLLHMLKDDRLGQH	ubiquitination	[1]
166	GKGNVTLKELNARPM	ubiquitination	[1, 2]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

 Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; GTP-binding; Nucleotide-binding; Protein transport; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 198 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IDA:HPA.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
 GO:0016529; C:sarcoplasmic reticulum; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR006689; Small_GTPase_ARF/SAR.
 IPR006687; Small_GTPase_SAR1. 

Pfam

 PF00025; Arf 

SMART

 SM00178; SAR 

PROSITE

 PS51422; SAR1 

PRINTS

 PR00328; SAR1GTPBP.