CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029664
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 RNA binding protein fox-1 homolog 
Protein Synonyms/Alias
  
Gene Name
 RBM9 
Gene Synonyms/Alias
 RBFOX2 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
131IFNERGSKGFGFVTFubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
 RNA-binding protein that regulates alternative splicing events (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; mRNA processing; mRNA splicing; Nucleus; Reference proteome; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 357 AA 
Protein Sequence
MVQPFTTIPF PPPPQNGIPT EYGVPHTQDY AGQTGEHNLT LYGSTQAHGE QSSNSPSTQN 60
GSLTQTEGGA QTDGQQSQTQ SSENSESKST PKRLHVSNIP FRFRDPDLRQ MFGQFGKILD 120
VEIIFNERGS KGFGFVTFEN SADADRAREK LHGTVVEGRK IEVNNATARV MTNKKMVTPY 180
ANGWKLSPVV GAVYGPELYA ASSFQADVSL GNDAAVPLSG RGGINTYIPL IIPGFPYPTA 240
ATTAAAFRGA HLRGRGRTVY GAVRAVPPTA IPAYPGVVYQ DGFYGADLYG GYAAYRYAQP 300
ATATAATAAA AAAAAYSDGY GRVYTADPYH ALAPAASYGV GAVASLYRGG YSRFAPY 357 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
 GO:0043484; P:regulation of RNA splicing; IEA:InterPro.
 GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. 
Interpro
 IPR025670; Fox-1_C_dom.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR017325; RNA-bd_Fox-1.
 IPR000504; RRM_dom. 
Pfam
 PF12414; Fox-1_C
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS