UniProt Accession

 D3YZ08_MOUSE; D3YZ08 

Genbank Protein ID

 AC123868 

Genbank Nucleotide ID

  

Protein Name

 Telomeric repeat-binding factor 2 

Protein Synonyms/Alias

  

Gene Name

 Terf2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
336	RTLKAAFKALSTAQD	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 540 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0001673; C:male germ cell nucleus; IDA:MGI.
 GO:0030870; C:Mre11 complex; IEA:Compara.
 GO:0000784; C:nuclear chromosome, telomeric region; IDA:MGI.
 GO:0000783; C:nuclear telomere cap complex; IEA:Compara.
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0042162; F:telomeric DNA binding; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0032205; P:negative regulation of telomere maintenance; IEA:Compara.
 GO:0032206; P:positive regulation of telomere maintenance; IDA:MGI.
 GO:0031848; P:protection from non-homologous end joining at telomere; IDA:MGI.
 GO:0070198; P:protein localization to chromosome, telomeric region; IEA:Compara.
 GO:0010834; P:telomere maintenance via telomere shortening; IEA:Compara.
 GO:0031627; P:telomeric loop formation; IEA:Compara. 

Interpro

 IPR009057; Homeodomain-like.
 IPR017930; Myb_dom.
 IPR001005; SANT/Myb.
 IPR017357; Telomere_repeat-bd-1/2.
 IPR013867; Telomere_rpt-bd_fac_dimer_dom. 

Pfam

 PF00249; Myb_DNA-binding
 PF08558; TRF 

SMART

 SM00717; SANT 

PROSITE

 PS51294; HTH_MYB 

PRINTS