CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026579
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BK150C2.9 protein 
Protein Synonyms/Alias
 DNA dC->dU-editing enzyme APOBEC-3D; HCG41704, isoform CRA_b 
Gene Name
 bK150C2.9 
Gene Synonyms/Alias
 APOBEC3D; hCG_41704 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
62FRGPVLPKRQSNHRQubiquitination[1]
163SVKIMGYKDFVSCWKubiquitination[1]
181YSDDEPFKPWKGLQTubiquitination[1, 2, 3]
184DEPFKPWKGLQTNFRubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 202 AA 
Protein Sequence
MNPQIRNPME RMYRDTFYDN FENEPILYGR SYTWLCYEVK IKRGRSNLLW DTGVFRGPVL 60
PKRQSNHRQE VDPETHCHAE RCFLSWFCDD ILSPNTNYEV TWYTSWSPCP ECAGEVAEFL 120
ARHSNVNLTI FTARLCYFWD TDYQEGLCSL SQEGASVKIM GYKDFVSCWK NFVYSDDEPF 180
KPWKGLQTNF RLLKRRLREI LQ 202 
Gene Ontology
 GO:0016814; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC. 
Interpro
 IPR016192; APOBEC/CMP_deaminase_Zn-bd.
 IPR013158; APOBEC_N.
 IPR016193; Cytidine_deaminase-like. 
Pfam
 PF08210; APOBEC_N 
SMART
  
PROSITE
 PS00903; CYT_DCMP_DEAMINASES 
PRINTS