UniProt Accession

 PA1B2_MOUSE; Q61206; Q6PKE6; Q7TNP3 

Genbank Protein ID

 U57747; AK153424; BC002037; BC056211 

Genbank Nucleotide ID

 AAC52997.1; BAE31983.1; AAH02037.1; AAH56211.1 

Protein Name

 Platelet-activating factor acetylhydrolase IB subunit beta 

Protein Synonyms/Alias

 PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH subunit beta 

Gene Name

 Pafah1b2 

Gene Synonyms/Alias

 Pafahb 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
161	AKVNQLLKVSLPKLA	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit. 

Sequence Annotation

 ACT_SITE 48 48 By similarity.
 ACT_SITE 193 193 By similarity.
 ACT_SITE 196 196 By similarity.
 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 2 2 Phosphoserine (By similarity).  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Lipid degradation; Lipid metabolism; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 229 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:EC.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0006928; P:cellular component movement; TAS:ProtInc.
 GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
 GO:0016239; P:positive regulation of macroautophagy; IEA:Compara.
 GO:0007283; P:spermatogenesis; IMP:MGI. 

Interpro

 IPR013831; SGNH_hydro-type_esterase_dom. 

Pfam

  

SMART

  

PROSITE

 PS01098; LIPASE_GDSL_SER 

PRINTS