UniProt Accession

 B4DP62_HUMAN; B4DP62 

Genbank Protein ID

 AC004463; AK298204; CH471176; CH471176; CH471176 

Genbank Nucleotide ID

 BAG60474.1; EAX03049.1; EAX03050.1; EAX03051.1 

Protein Name

 Solute carrier family 25 (Mitochondrial carrier; citrate transporter), member 1, isoform CRA_b 

Protein Synonyms/Alias

 Tricarboxylate transport protein, mitochondrial; cDNA FLJ60026, highly similar to Tricarboxylate transport protein, mitochondrial 

Gene Name

 SLC25A1 

Gene Synonyms/Alias

 hCG_17246 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
57	DQTSPNPKYRGFFHG	ubiquitination	[1]
75	IVREQGLKGTYQGLT	ubiquitination	[1]
87	GLTATVLKQGSNQAI	ubiquitination	[1, 2]
152	MQGLEAHKYRNTWDC	acetylation	[3]
152	MQGLEAHKYRNTWDC	ubiquitination	[1, 4]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 208 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 

Interpro

 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 

Pfam

 PF00153; Mito_carr 

SMART

  

PROSITE

 PS50920; SOLCAR 

PRINTS